AIMC Topic: Endothelium

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3D electron microscopy for analyzing nanoparticles in the tumor endothelium.

Proceedings of the National Academy of Sciences of the United States of America Dec 12, 2024
Delivering medical agents to diseased tissues has been challenging, leading researchers to study the in vivo transport process in the body for improving delivery. Many imaging techniques exist for mapping the distribution of medical agent-carrying na...
Humans Machine Learning Animals Neoplasms Cell Line, Tumor Imaging, Three-Dimensional Mice Nanoparticles Microscopy, Electron Endothelial Cells Endothelium
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Application of Machine-Learning Methods to Recognize mitoBK Channels from Different Cell Types Based on the Experimental Patch-Clamp Results.

International journal of molecular sciences Jan 15, 2021
(1) Background: In this work, we focus on the activity of large-conductance voltage- and Ca2+-activated potassium channels (BK) from the inner mitochondrial membrane (mitoBK). The characteristic electrophysiological features of the mitoBK channels ar...
Neural Networks, Computer Artificial Intelligence Machine Learning Algorithms Pregnancy Female Animals Rats, Wistar Rats Fibroblasts Kinetics Mitochondria Hippocampus Protein Conformation Endothelium Pregnancy, Animal Ion Channel Gating Patch-Clamp Techniques Large-Conductance Calcium-Activated Potassium Channels Potassium Channels
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Regional arterial stiffness in central and peripheral arteries is differentially related to endothelial dysfunction assessed by brachial flow-mediated dilation in metabolic syndrome.

Diabetes & vascular disease research Dec 28, 2017
The interrelationship between endothelial function and arterial stiffness may be different for central and peripheral arteries due to their structural and functional differences. The study aims to assess the interrelationship between central and peri...
Humans Female Risk Factors Aged Male Middle Aged Hemodynamics Metabolic Syndrome Blood Pressure Vascular Stiffness Pulse Wave Analysis Vascular Diseases Carotid Arteries Brachial Artery Blood Flow Velocity Endothelium
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