AIMC Topic: Precision Medicine

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Big Data Cohort Extraction for Personalized Statin Treatment and Machine Learning.

Methods in molecular biology (Clifton, N.J.)
The creation of big clinical data cohorts for machine learning and data analysis require a number of steps from the beginning to successful completion. Similar to data set preprocessing in other fields, there is an initial need to complete data quali...

Machine-learning-based patient-specific prediction models for knee osteoarthritis.

Nature reviews. Rheumatology
Osteoarthritis (OA) is an extremely common musculoskeletal disease. However, current guidelines are not well suited for diagnosing patients in the early stages of disease and do not discriminate patients for whom the disease might progress rapidly. T...

Radiomics with artificial intelligence for precision medicine in radiation therapy.

Journal of radiation research
Recently, the concept of radiomics has emerged from radiation oncology. It is a novel approach for solving the issues of precision medicine and how it can be performed, based on multimodality medical images that are non-invasive, fast and low in cost...

PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient.

JCO clinical cancer informatics
PURPOSE: The majority of patients with cancer receive treatments that are minimally informed by omics data. We propose a precision medicine computational framework, PANOPLY (Precision Cancer Genomic Report: Single Sample Inventory), to identify and p...

Machine learning: from radiomics to discovery and routine.

Der Radiologe
Machine learning is rapidly gaining importance in radiology. It allows for the exploitation of patterns in imaging data and in patient records for a more accurate and precise quantification, diagnosis, and prognosis. Here, we outline the basics of ma...

Machine learning and genomics: precision medicine versus patient privacy.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Machine learning can have a major societal impact in computational biology applications. In particular, it plays a central role in the development of precision medicine, whereby treatment is tailored to the clinical or genetic features of the patient...

Rise of the machines? Machine learning approaches and mental health: opportunities and challenges.

The British journal of psychiatry : the journal of mental science
Machine learning methods are being increasingly applied to physical healthcare. In this article we describe some of the potential benefits, challenges and limitations of this approach in a mental health context. We provide a number of examples where ...

[Artificial intelligence in psychiatry-an overview].

Der Nervenarzt
Artificial intelligence and the underlying methods of machine learning and neuronal networks (NN) have made dramatic progress in recent years and have allowed computers to reach superhuman performance in domains that used to be thought of as uniquely...