AIMC Topic: Proton Pump Inhibitors

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An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor.

Magnesium research Dec 1, 2015
PURPOSE: Magnesium is an important electrolyte for very many cell functions and its deficiency may lead to a wide spectrum of diseases. We report a clinical case of hypomagnesemia resulting from the chronic use of a proton pump inhibitor (PPI). PPIs ...
Hypocalcemia Metabolic Diseases Arrhythmias, Cardiac Hypoparathyroidism Omeprazole Proton Pump Inhibitors Down-Regulation Diagnosis, Differential Magnesium Predictive Value of Tests Electrocardiography Treatment Outcome Aged Biomarkers Humans Risk Factors Female Paresthesia
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Long-term Stability of Esomeprazole in 5% Dextrose Infusion Polyolefin Bags at 5 degrees C +/- 3 degrees C after Microwave Freeze-thaw Treatment.

International journal of pharmaceutical compounding Jan 1, 2015
To improve quality assurance, security, time management, and cost saving of drug delivery, preparation in advance of intravenous solutions has been developed for several infusion solutions. The objective of this study was to investigate the stability...
Proton Pump Inhibitors Spectrophotometry, Ultraviolet Esomeprazole Freezing Drug Compounding Chemistry, Pharmaceutical Polyenes Infusions, Intravenous Cold Temperature Glucose Technology, Pharmaceutical Time Factors Equipment Design Drug Packaging Drug Stability Hydrogen-Ion Concentration Chromatography, High Pressure Liquid Excipients Chromatography, Reverse-Phase Dosage Forms Asepsis Microwaves
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[HIGH FREQUENCY OF CYP2C19 ULTRARAPID METABOLIZERS IN RUSSIAN PATIENTS WITH PEPTIC ULCER].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Jan 1, 2015
INTRODUCTION: The main enzyme responsible for metabolism of proton pump inhibitors (PPI) is cytochrome P-4502C19 (CYP2C19). Among all CYP2C19 polymorphisms ulrarapid CYP2C19*17 allele plays an important role in clinical practice as in CYP2C19*17 alle...
Gene Frequency Adult Polymorphism, Genetic Female Genotype Cytochrome P-450 CYP2C19 Peptic Ulcer Middle Aged Moscow Male Proton Pump Inhibitors Retrospective Studies Humans
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