BACKGROUND: Radiation-induced pneumonitis affects up to 33% of non-small cell lung cancer (NSCLC) patients, with fatal pneumonitis occurring in 2% of patients. Pneumonitis risk is related to the dose and volume of lung irradiated. Clinical radiothera...
BACKGROUND: Hyperpolarized gas MRI is a functional lung imaging modality capable of visualizing regional lung ventilation with exceptional detail within a single breath. However, this modality requires specialized equipment and exogenous contrast, wh...
Background Hyperpolarized noble gas MRI helps measure lung ventilation, but clinical translation remains limited. Free-breathing proton MRI may help quantify lung function using existing MRI systems without contrast material and may assist in providi...
PURPOSE: The purpose of this study is to develop a deep learning (DL) method for producing four-dimensional computed tomography (4DCT) ventilation imaging and to evaluate the accuracy of the DL-based ventilation imaging against single-photon emission...
Background Fixed airflow limitation and ventilation heterogeneity are common in chronic obstructive pulmonary disease (COPD). Conventional noncontrast CT provides airway and parenchymal measurements but cannot be used to directly determine lung funct...
First and second ventilatory thresholds (VT and VT) represent the boundaries of the moderate-heavy and heavy-severe exercise intensity. Currently, VTs are primarily detected visually from cardiopulmonary exercise test (CPET) data, beginning with an i...
PURPOSE: Ventilation images can be derived from four-dimensional computed tomography (4DCT) by analyzing the change in HU values and deformable vector fields between different respiration phases of computed tomography (CT). As deformable image regist...
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