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Radiotherapy Dosage

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Error detection using a convolutional neural network with dose difference maps in patient-specific quality assurance for volumetric modulated arc therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
The aim of this study was to evaluate the use of dose difference maps with a convolutional neural network (CNN) to detect multi-leaf collimator (MLC) positional errors in patient-specific quality assurance for volumetric modulated radiation therapy (...

Conventional vs machine learning-based treatment planning in prostate brachytherapy: Results of a Phase I randomized controlled trial.

Brachytherapy
PURPOSE: The purpose of this study was to evaluate the noninferiority of Day 30 dosimetry between a machine learning-based treatment planning system for prostate low-dose-rate (LDR) brachytherapy and the conventional, manual planning technique. As a ...

A method of using deep learning to predict three-dimensional dose distributions for intensity-modulated radiotherapy of rectal cancer.

Journal of applied clinical medical physics
PURPOSE: To develop and test a three-dimensional (3D) deep learning model for predicting 3D voxel-wise dose distributions for intensity-modulated radiotherapy (IMRT).

DeepDose: Towards a fast dose calculation engine for radiation therapy using deep learning.

Physics in medicine and biology
We present DeepDose, a deep learning framework for fast dose calculations in radiation therapy. Given a patient anatomy and linear-accelerator IMRT multi-leaf-collimator shape or segment, a novel set of physics-based inputs is calculated that encode ...

A convolution neural network for higher resolution dose prediction in prostate volumetric modulated arc therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: This study aims to investigate the feasibility of using convolutional neural networks to predict an accurate and high resolution dose distribution from an approximated and low resolution input dose.

The importance of evaluating the complete automated knowledge-based planning pipeline.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
We determine how prediction methods combine with optimization methods in two-stage knowledge-based planning (KBP) pipelines to produce radiation therapy treatment plans. We trained two dose prediction methods, a generative adversarial network (GAN) a...

Artificial neural networks allow response prediction in squamous cell carcinoma of the scalp treated with radiotherapy.

Journal of the European Academy of Dermatology and Venereology : JEADV
BACKGROUND: Epithelial neoplasms of the scalp account for approximately 2% of all skin cancers and for about 10-20% of the tumours affecting the head and neck area. Radiotherapy is suggested for localized cutaneous squamous cell carcinomas (cSCC) wit...

Multi-sequence MR image-based synthetic CT generation using a generative adversarial network for head and neck MRI-only radiotherapy.

Medical physics
PURPOSE: The purpose of this study is to investigate the effect of different magnetic resonance (MR) sequences on the accuracy of deep learning-based synthetic computed tomography (sCT) generation in the complex head and neck region.

Performance assessment of a new optimization system for robotic SBRT MLC-based plans.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To assess the performance of a new optimization system, VOLO, for CyberKnife MLC-based SBRT plans in comparison with the existing Sequential optimizer.

Many-isocenter optimization for robotic radiotherapy.

Physics in medicine and biology
Despite significant dosimetric gains, clinical implementation of the 4π non-coplanar radiotherapy on the widely available C-arm gantry system is hindered by limited clearance, and the need to perform complex coordinated gantry and couch motion. A rob...