AI Medical Compendium Topic:
Radiotherapy Planning, Computer-Assisted

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Technical Note: Dose prediction for radiation therapy using feature-based losses and One Cycle Learning.

Medical physics
PURPOSE: To present the technical details of the runner-up model in the open knowledge-based planning (OpenKBP) challenge for the dose-volume histogram (DVH) stream. The model was designed to ensure simple and reproducible training, without the neces...

Independent verification of brachytherapy treatment plan by using deep learning inference modeling.

Physics in medicine and biology
This study aims to develop a deep learning-based strategy for treatment plan check and verification of high-dose rate (HDR) brachytherapy. A deep neural network was trained to verify the dwell positions and times for a given input brachytherapy isodo...

Implementation of deep learning-based auto-segmentation for radiotherapy planning structures: a workflow study at two cancer centers.

Radiation oncology (London, England)
PURPOSE: We recently described the validation of deep learning-based auto-segmented contour (DC) models for organs at risk (OAR) and clinical target volumes (CTV). In this study, we evaluate the performance of implemented DC models in the clinical ra...

Synthetic CT generation from CBCT images via unsupervised deep learning.

Physics in medicine and biology
Adaptive-radiation-therapy (ART) is applied to account for anatomical variations observed over the treatment course. Daily or weekly cone-beam computed tomography (CBCT) is commonly used in clinic for patient positioning, but CBCT's inaccuracy in Hou...

Automatic clinical target volume delineation for cervical cancer in CT images using deep learning.

Medical physics
PURPOSE: Accurately delineating clinical target volumes (CTV) is essential for completing radiotherapy plans but is time-consuming, labor-intensive, and prone to inter-observer variation. Automating CTV delineation has the benefits of both speeding u...

Artificial Intelligence in magnetic Resonance guided Radiotherapy: Medical and physical considerations on state of art and future perspectives.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Over the last years, technological innovation in Radiotherapy (RT) led to the introduction of Magnetic Resonance-guided RT (MRgRT) systems. Due to the higher soft tissue contrast compared to on-board CT-based systems, MRgRT is expected to significant...

A deep learning-based framework for segmenting invisible clinical target volumes with estimated uncertainties for post-operative prostate cancer radiotherapy.

Medical image analysis
In post-operative radiotherapy for prostate cancer, precisely contouring the clinical target volume (CTV) to be irradiated is challenging, because the cancerous prostate gland has been surgically removed, so the CTV encompasses the microscopic spread...

Deep-learning-based image registration and automatic segmentation of organs-at-risk in cone-beam CT scans from high-dose radiation treatment of pancreatic cancer.

Medical physics
PURPOSE: Accurate deformable registration between computed tomography (CT) and cone-beam CT (CBCT) images of pancreatic cancer patients treated with high biologically effective radiation doses is essential to assess changes in organ-at-risk (OAR) loc...

Improving CBCT quality to CT level using deep learning with generative adversarial network.

Medical physics
PURPOSE: To improve image quality and computed tomography (CT) number accuracy of daily cone beam CT (CBCT) through a deep learning methodology with generative adversarial network.

Metrics to evaluate the performance of auto-segmentation for radiation treatment planning: A critical review.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Advances in artificial intelligence-based methods have led to the development and publication of numerous systems for auto-segmentation in radiotherapy. These systems have the potential to decrease contour variability, which has been associated with ...