AIMC Topic: Renal Insufficiency, Chronic

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Modulation of aldosterone levels by aldosterone synthase promoter polymorphism and association with eGFR decline in patients with chronic kidney disease.

Discovery medicine Dec 1, 2018
To determine whether -344T/C CYP11B2 promoter polymorphism affects serum aldosterone levels and whether this polymorphism is an indicator of eGFR decline in patients with chronic kidney disease. -344 C/T CYP11B2 gene polymorphism analysis was perform...
Disease Progression Cerebrovascular Disorders Humans Polymorphism, Single Nucleotide Down-Regulation Female Renal Insufficiency, Chronic Cytochrome P-450 CYP11B2 Glomerular Filtration Rate Aged Follow-Up Studies Adult Aldosterone Male Cardiovascular Diseases Middle Aged Promoter Regions, Genetic
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Risk factors for diastolic left ventricular myocardial dysfunction in patients with chronic kidney disease.

Terapevticheskii arkhiv Sep 20, 2018
AIM: To examine the frequency and risk factors for the development of diastolic dysfunction (DD) of the left ventricle (LV) of the heart in patients with chronic kidney disease (CKD).
Patient Acuity Humans Middle Aged Ventricular Remodeling Female Disease Progression Ventricular Dysfunction, Left Risk Factors Incidence Russia Male Renal Insufficiency, Chronic Hypertrophy, Left Ventricular Echocardiography Glomerular Filtration Rate Cystatin C
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Chronic Kidney Disease: Detection and Evaluation.

American family physician Dec 15, 2017
Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. Because this disease can silently progress to advanced stages, early detection is critical for initi...
Severity of Illness Index Renal Insufficiency, Chronic Glomerular Filtration Rate Creatinine Referral and Consultation Practice Guidelines as Topic Female Risk Factors Adult Male Humans Risk Assessment Biomarkers Disease Progression Prognosis
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The dose-response association between estimated glomerular filtration rate and prognosis of patients with ST-segment elevation myocardial infarction from rural areas of China's Liaoning province.

Medicine Dec 1, 2017
We aimed to investigate the dose-response associations between chronic kidney disease (CKD), and short and long-term cardiovascular outcomes, to characterize these associations by drawing dose-response curves based on a Chinese rural ST-segment eleva...
Humans Biomarkers Prognosis Female Aged Aged, 80 and over Glomerular Filtration Rate China Adult Hospital Mortality Age Factors Male Logistic Models ST Elevation Myocardial Infarction Cardiovascular Diseases Hyperlipidemias Membrane Proteins Middle Aged Drosophila Proteins Rural Population Comorbidity Proportional Hazards Models Renal Insufficiency, Chronic Severity of Illness Index
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Metabolic acidosis of chronic kidney disease and subclinical cardiovascular disease markers: Friend or foe?

Medicine Nov 1, 2017
The effect of chronic metabolic acidosis (MA) on cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) is largely unknown. Therefore, we aimed to study this relationship in nondialysis CKD patients.This cross-sectional, single-c...
Triglycerides Acidosis Bicarbonates Vascular Calcification Renal Insufficiency, Chronic Humans Glomerular Filtration Rate Prospective Studies Cross-Sectional Studies Cholesterol Biomarkers Male Ankle Brachial Index Female Cardiovascular Diseases Carotid Intima-Media Thickness Risk Factors Middle Aged Phosphates Aged Logistic Models
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Selection and Short-Term Outcomes of Living Kidney Donors in Singapore - An Analysis of the Donor Care Registry.

Annals of the Academy of Medicine, Singapore Nov 1, 2017
INTRODUCTION: Transplant rates in Singapore have been falling and there is limited information on baseline characteristics and clinical outcomes of living kidney donors nationally. This study aimed to determine the safety of living kidney donor trans...
Mortality Lost to Follow-Up Kidney Failure, Chronic Singapore Registries Proportional Hazards Models Multivariate Analysis Nephrectomy Humans Kidney Transplantation Postoperative Complications Renal Insufficiency, Chronic Glomerular Filtration Rate Follow-Up Studies Age Factors Living Donors
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Arterial stiffness and 25-hydroxyvitamin D levels in chronic kidney disease patients.

Revista da Associacao Medica Brasileira (1992) Oct 1, 2017
OBJECTIVE: Arterial stiffness refers to arterial wall rigidity, particularly developing in central vessels. Arterial stiffness increases in early stage chronic kidney disease (CKD), and it is a strong predictor of cardiovascular and all cause mortali...
Humans Female Aged Cross-Sectional Studies Vitamin D Vitamin D Deficiency Blood Pressure Vascular Stiffness Pulse Wave Analysis Reference Values Male Middle Aged Prevalence Time Factors Renal Insufficiency, Chronic Glomerular Filtration Rate Turkey Sex Factors Radioimmunoassay Reference Standards Statistics, Nonparametric
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Does advanced chronic kidney disease impact transjugular intrahepatic portosystemic shunt efficacy and safety?

Acta gastro-enterologica Belgica Jan 1, 2017
BACKGROUND AND STUDY AIMS: There are currently limited data available summarizing the clinical outcomes and safety of transjugular intrahepatic portosystemic shunts (TIPS) in cases of advanced chronic kidney disease (CKD). The study aimed to assess e...
Paracentesis Portasystemic Shunt, Transjugular Intrahepatic Humans Female Glomerular Filtration Rate Male Ascites Middle Aged Diuretics Severity of Illness Index Gastrointestinal Hemorrhage Incidence Hepatic Encephalopathy Renal Insufficiency, Chronic Illinois Treatment Outcome
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Prevalence and risk factors of chronic kidney disease in an african semi-urban area: Results from a cross-sectional survey in Gueoul, Senegal.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Jan 1, 2017
Chronic kidney disease (CKD) is a public health priority worldwide; however, its prevalence and incidence are difficult to assess. In Africa, few studies have been conducted on the prevalence of CKD. This study sought to describe the epidemiological ...
Urban Health Metabolic Syndrome Cross-Sectional Studies Obesity Male Proteinuria Middle Aged Senegal Risk Assessment Humans Health Surveys Prevalence Female Kidney Severity of Illness Index Risk Factors Hypertension Aged Renal Insufficiency, Chronic Aged, 80 and over Glomerular Filtration Rate Adult Diabetes Mellitus
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Lactate levels and risk of lactic acidosis with metformin in diabetic kidney disease patients.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Jan 1, 2017
Metformin as an oral antidiabetic drug (OAD) is not recommended in renal failure due to the presumed risk of lactic acidosis though it has advantages in cardiovascular protection with a low risk of hypoglycemia. Few studies have measured lactic acid ...
Biomarkers Female Risk Factors Male Middle Aged Risk Assessment Humans Hydrogen-Ion Concentration Administration, Oral Metformin Lactic Acid Bicarbonates Acidosis, Lactic Case-Control Studies Diabetes Mellitus, Type 2 Diabetic Nephropathies Hypoglycemic Agents Renal Insufficiency, Chronic Treatment Outcome
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