AIMC Topic: Research Design

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Combined application of mixture experimental design and artificial neural networks in the solid dispersion development.

Drug development and industrial pharmacy Jun 11, 2015
This study for the first time demonstrates combined application of mixture experimental design and artificial neural networks (ANNs) in the solid dispersions (SDs) development. Ternary carbamazepine-Soluplus®-poloxamer 188 SDs were prepared by solven...
Neural Networks, Computer Research Design Polyvinyls Poloxamer Polyethylene Glycols Chemistry, Pharmaceutical
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Adaptive Neural Output Feedback Control of Output-Constrained Nonlinear Systems With Unknown Output Nonlinearity.

IEEE transactions on neural networks and learning systems Apr 24, 2015
This paper addresses the problem of adaptive neural output-feedback control for a class of special nonlinear systems with the hysteretic output mechanism and the unmeasured states. A modified Bouc-Wen model is first employed to capture the output hys...
Neural Networks, Computer Algorithms Nonlinear Dynamics Research Design Computer Simulation Feedback
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Laparoscopic and Robotic-assisted Vesicovaginal Fistula Repair: A Systematic Review of the Literature.

Journal of minimally invasive gynecology Mar 10, 2015
Two types of laparoscopic or robotic-assisted vesicovaginal fistula (VVF) repairs, the traditional transvesical (O'Conor) and extravesical techniques, dominate the literature. The objectives of this study are to compare success rates between laparosc...
Urologic Surgical Procedures Surgical Flaps Abdominal Cavity Retrospective Studies Female Aged Robotics Laparoscopy Vesicovaginal Fistula Humans Research Design
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Use of uniform designs in combination with neural networks for viral infection process development.

Biotechnology progress Jan 27, 2015
This work aimed to compare the predictive capacity of empirical models, based on the uniform design utilization combined to artificial neural networks with respect to classical factorial designs in bioprocess, using as example the rabies virus replic...
Cricetinae Animals Virus Cultivation Neural Networks, Computer Biotechnology Cell Line Research Design Rabies virus Virus Replication
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Secondary use of electronic health records for building cohort studies through top-down information extraction.

Journal of biomedical informatics Nov 21, 2014
Controlled clinical trials are usually supported with an in-front data aggregation system, which supports the storage of relevant information according to the trial context within a highly structured environment. In contrast to the documentation of c...
United States Europe Natural Language Processing Data Mining Information Storage and Retrieval Software Medical Informatics Algorithms Computer Graphics Reproducibility of Results Research Design Databases, Factual User-Computer Interface Humans Electronic Health Records Cohort Studies
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Citations alone were enough to predict favorable conclusions in reviews of neuraminidase inhibitors.

Journal of clinical epidemiology Oct 22, 2014
OBJECTIVES: To examine the use of supervised machine learning to identify biases in evidence selection and determine if citation information can predict favorable conclusions in reviews about neuraminidase inhibitors.
Publications Influenza, Human Selection Bias Humans Research Design Artificial Intelligence Neuraminidase Review Literature as Topic Enzyme Inhibitors
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A multi-technique approach to bridge electronic case report form design and data standard adoption.

Journal of biomedical informatics Sep 6, 2014
BACKGROUND AND OBJECTIVE: The importance of data standards when integrating clinical research data has been recognized. The common data element (CDE) is a consensus-based data element for data harmonization and sharing between clinical researchers, i...
Information Storage and Retrieval Models, Statistical Natural Language Processing Biomarkers Reproducibility of Results Biomedical Research Computer Systems Computational Biology Parkinson Disease Software Algorithms Research Design Humans
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[Artificial intelligence for randomized controlled trials in cardiology: applications and future perspectives].

Giornale italiano di cardiologia (2006) Aug 1, 2025
Integrating artificial intelligence (AI) into cardiovascular clinical trials is emerging as a key factor in streamlining patient selection, data collection, endpoint monitoring, and outcome analysis. On the one hand, machine learning and deep learnin...
Humans Artificial Intelligence Cardiovascular Diseases Randomized Controlled Trials as Topic Cardiology Machine Learning Algorithms Research Design
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A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations.

Acta anaesthesiologica Scandinavica Jul 1, 2025
BACKGROUND: Sepsis is a leading cause of mortality worldwide, characterized by a dysregulated host response to infection. Despite the development of multiple clinical practice guidelines (CPGs) to standardize sepsis management, substantial variabilit...
Practice Guidelines as Topic Research Design Sepsis Systematic Reviews as Topic Humans
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Artificial intelligence for difficult airway assessment: a protocol for a systematic review with meta-analysis.

BMJ open Jun 10, 2025
INTRODUCTION: Identifying difficult airways and avoiding unanticipated difficult airways through difficult airway assessment are crucial for patient safety prior to airway management. Therefore, accurately predicting difficult airways through airway ...
Artificial Intelligence Research Design Systematic Reviews as Topic Meta-Analysis as Topic Humans Airway Management
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