AIMC Topic: Ribonucleotides

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A comparison of machine learning techniques for classification of HIV patients with antiretroviral therapy-induced mitochondrial toxicity from those without mitochondrial toxicity.

BMC medical research methodology Nov 27, 2019
BACKGROUND: Antiretroviral therapy (ART) has significantly reduced HIV-related morbidity and mortality. However, therapeutic benefit of ART is often limited by delayed drug-associated toxicity. Nucleoside reverse transcriptase inhibitors (NRTIs) are ...
Humans Machine Learning Algorithms Biomarkers Case-Control Studies HIV Infections Anti-Retroviral Agents Deoxyribonucleotides Ribonucleotides Dideoxynucleotides
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PRIdictor: Protein-RNA Interaction predictor.

Bio Systems Dec 1, 2015
Several computational methods have been developed to predict RNA-binding sites in protein, but its inverse problem (i.e., predicting protein-binding sites in RNA) has received much less attention. Furthermore, most methods that predict RNA-binding si...
Computational Biology Support Vector Machine Proteins Amino Acids RNA Binding Sites Ribonucleotides
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Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.

Scientific reports Nov 18, 2015
Endogenous ribonucleotides and deoxyribonucleotides are essential metabolites that play important roles in a broad range of key cellular functions. Their intracellular levels could also reflect the action of nucleoside analogues. We investigated the ...
Humans Neural Networks, Computer Hep G2 Cells Cell Survival Chromatography, Liquid Metabolic Networks and Pathways Models, Biological Fluorouracil Tandem Mass Spectrometry Inhibitory Concentration 50 Adenine Nucleotides Cytosine Nucleotides Deoxyribonucleotides Guanine Nucleotides Ribonucleotides Thymine Nucleotides Uracil Nucleotides
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