AIMC Topic: RNA, Long Noncoding

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LncLocation: Efficient Subcellular Location Prediction of Long Non-Coding RNA-Based Multi-Source Heterogeneous Feature Fusion.

International journal of molecular sciences Oct 1, 2020
Recent studies uncover that subcellular location of long non-coding RNAs (lncRNAs) can provide significant information on its function. Due to the lack of experimental data, the number of lncRNAs is very limited, experimentally verified subcellular l...
Datasets as Topic Cell Nucleus Gene Expression Regulation RNA, Long Noncoding Benchmarking Exosomes Cytoplasm Ribosomes Eukaryotic Cells Base Sequence Genome, Human Terminology as Topic Humans Software Animals Computational Biology Support Vector Machine Databases, Genetic
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LncMirNet: Predicting LncRNA-miRNA Interaction Based on Deep Learning of Ribonucleic Acid Sequences.

Molecules (Basel, Switzerland) Sep 23, 2020
Long non-coding RNA (LncRNA) and microRNA (miRNA) are both non-coding RNAs that play significant regulatory roles in many life processes. There is cumulating evidence showing that the interaction patterns between lncRNAs and miRNAs are highly related...
RNA, Messenger Deep Learning Time Factors Sequence Analysis, RNA Computational Biology RNA, Long Noncoding
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lncRNA_Mdeep: An Alignment-Free Predictor for Distinguishing Long Non-Coding RNAs from Protein-Coding Transcripts by Multimodal Deep Learning.

International journal of molecular sciences Jul 23, 2020
Long non-coding RNAs (lncRNAs) play crucial roles in diverse biological processes and human complex diseases. Distinguishing lncRNAs from protein-coding transcripts is a fundamental step for analyzing the lncRNA functional mechanism. However, the exp...
Humans Mice RNA, Long Noncoding Databases, Nucleic Acid Software Animals Deep Learning
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LPI-CNNCP: Prediction of lncRNA-protein interactions by using convolutional neural network with the copy-padding trick.

Analytical biochemistry May 23, 2020
Long noncoding RNAs (lncRNAs) play critical roles in many pathological and biological processes, such as post-transcription, cell differentiation and gene regulation. Increasingly more studies have shown that lncRNAs function through mainly interacti...
Neural Networks, Computer RNA-Binding Proteins RNA, Long Noncoding Amino Acid Sequence Humans
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A novel graph attention adversarial network for predicting disease-related associations.

Methods (San Diego, Calif.) May 21, 2020
Identifying complex human diseases at molecular level is very helpful, especially in diseases diagnosis, therapy, prognosis and monitoring. Accumulating evidences demonstrated that RNAs are playing important roles in identifying various complex human...
Deep Learning Genetic Association Studies MicroRNAs Datasets as Topic Gene Regulatory Networks Computational Biology RNA, Long Noncoding Gene Expression Regulation Genetic Predisposition to Disease Databases, Genetic Predictive Value of Tests
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Multi-feature fusion for deep learning to predict plant lncRNA-protein interaction.

Genomics May 11, 2020
Long non-coding RNAs (lncRNAs) play key roles in regulating cellular biological processes through diverse molecular mechanisms including binding to RNA binding proteins. The majority of plant lncRNAs are functionally uncharacterized, thus, accurate p...
Plant Proteins Arabidopsis RNA, Plant RNA, Long Noncoding Zea mays Deep Learning RNA-Binding Proteins
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SDLDA: lncRNA-disease association prediction based on singular value decomposition and deep learning.

Methods (San Diego, Calif.) May 5, 2020
In recent years, accumulating studies have shown that long non-coding RNAs (lncRNAs) not only play an important role in the regulation of various biological processes but also are the foundation for understanding mechanisms of human diseases. Due to ...
Datasets as Topic Gene Expression Regulation Databases, Genetic RNA, Long Noncoding Data Mining Humans Neoplasms Deep Learning Genetic Predisposition to Disease Genetic Association Studies Computational Biology
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Machine Learning Supports Long Noncoding RNAs as Expression Markers for Endometrial Carcinoma.

BioMed research international Jan 10, 2020
Uterine corpus endometrial carcinoma (UCEC) is the second most common type of gynecological tumor. Several research studies have recently shown the potential of different ncRNAs as biomarkers for prognostics and diagnosis in different types of cancer...
Databases, Genetic RNA, Long Noncoding Endometrial Neoplasms Female Transcriptome Biomarkers, Tumor ROC Curve Gene Expression Profiling Gene Regulatory Networks Humans Machine Learning
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A gastric cancer LncRNAs model for MSI and survival prediction based on support vector machine.

BMC genomics Nov 13, 2019
BACKGROUND: Recent studies have shown that long non-coding RNAs (lncRNAs) play a crucial role in the induction of cancer through epigenetic regulation, transcriptional regulation, post-transcriptional regulation and other aspects, thus participating ...
RNA, Long Noncoding Microsatellite Instability Disease-Free Survival Humans Models, Genetic Prognosis Adenocarcinoma Kaplan-Meier Estimate Support Vector Machine Stomach Neoplasms Cohort Studies
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A classification model for lncRNA and mRNA based on k-mers and a convolutional neural network.

BMC bioinformatics Sep 13, 2019
BACKGROUND: Long-chain non-coding RNA (lncRNA) is closely related to many biological activities. Since its sequence structure is similar to that of messenger RNA (mRNA), it is difficult to distinguish between the two based only on sequence biometrics...
Chickens Animals Humans RNA, Long Noncoding Neural Networks, Computer Mice RNA, Messenger
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