AIMC Topic: SARS-CoV-2

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Leveraging Artificial Intelligence for Synergies in Drug Discovery: From Computers to Clinics.

Current pharmaceutical design
Over the period of the preceding decade, artificial intelligence (AI) has proved an outstanding performance in entire dimensions of science including pharmaceutical sciences. AI uses the concept of machine learning (ML), deep learning (DL), and neura...

Understanding the Manufacturing Process of Lipid Nanoparticles for mRNA Delivery Using Machine Learning.

Chemical & pharmaceutical bulletin
Lipid nanoparticles (LNPs), used for mRNA vaccines against severe acute respiratory syndrome coronavirus 2, protect mRNA and deliver it into cells, making them an essential delivery technology for RNA medicine. The LNPs manufacturing process consists...

DDA-SSNets: Dual decoder attention-based semantic segmentation networks for COVID-19 infection segmentation and classification using chest X-Ray images.

Journal of X-ray science and technology
BACKGROUND: COVID-19 needs to be diagnosed and staged to be treated accurately. However, prior studies' diagnostic and staging abilities for COVID-19 infection needed to be improved. Therefore, new deep learning-based approaches are required to aid r...

Combating COVID-19 Crisis using Artificial Intelligence (AI) Based Approach: Systematic Review.

Current topics in medicinal chemistry
BACKGROUND: SARS-CoV-2, the unique coronavirus that causes COVID-19, has wreaked damage around the globe, with victims displaying a wide range of difficulties that have encouraged medical professionals to look for innovative technical solutions and t...

Diagnosis of Covid-19 from CT slices using Whale Optimization Algorithm, Support Vector Machine and Multi-Layer Perceptron.

Journal of X-ray science and technology
BACKGROUND: The coronavirus disease 2019 is a serious and highly contagious disease caused by infection with a newly discovered virus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Determination of Novel SARS-CoV-2 Inhibitors by Combination of Machine Learning and Molecular Modeling Methods.

Medicinal chemistry (Shariqah (United Arab Emirates))
INTRODUCTION: Within the scope of the project, this study aimed to find novel inhibitors by combining computational methods. In order to design inhibitors, it was aimed to produce molecules similar to the RdRp inhibitor drug Favipiravir by using the ...

Application of artificial intelligence for the classification of the clinical outcome and therapy in patients with viral infections: The case of COVID-19.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: With the end of the coronavirus disease 2019 (COVID-19) pandemic, it becomes intriguing to observe the impact of innovative digital technologies on the diagnosis and management of diseases, in order to improve clinical outcomes for patien...

Unraveling viral drug targets: a deep learning-based approach for the identification of potential binding sites.

Briefings in bioinformatics
The coronavirus disease 2019 (COVID-19) pandemic has spurred a wide range of approaches to control and combat the disease. However, selecting an effective antiviral drug target remains a time-consuming challenge. Computational methods offer a promisi...

Adaptive learning embedding features to improve the predictive performance of SARS-CoV-2 phosphorylation sites.

Bioinformatics (Oxford, England)
MOTIVATION: The rapid and extensive transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented global health emergency, affecting millions of people and causing an immense socioeconomic impact. The id...