AIMC Topic: SARS-CoV-2

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Vaccination at a crossroad: science, politics and public trust.

Swiss medical weekly
Vaccine hesitancy threatens to erode one of medicine's greatest achievements. Recent measles outbreaks in Europe and the United States illustrate the consequences of declining confidence. At the centre lies misinformation, amplified through digital n...

Predicting COVID-19 patient recovery or mortality using deep neural decision tree and forest.

BMC research notes
OBJECTIVE: Identifying patients at high risk of mortality is crucial for emergency physicians to allocate hospital resources effectively, particularly in regions with limited medical services. This need becomes even more pressing during global health...

Improving outbreak forecasts through model augmentation.

Proceedings of the National Academy of Sciences of the United States of America
Accurate forecasts of disease outbreaks are critical for effective public health responses, management of healthcare surge capacity, and communication of public risk. There are a growing number of powerful forecasting methods that fall into two broad...

AI-Enhanced Lateral Flow Assay Enables 3-Minute Quantitative Detection with Laboratory-Grade Accuracy.

Analytical chemistry
Lateral flow immunoassay (LFA) remains one of the most widely used point-of-care testing (POCT) platforms for disease diagnosis, food safety assessment, and environmental monitoring. However, traditional LFAs typically require up to 30 min and offer ...

Mass spectrometry combined with machine learning identifies novel protein signatures as demonstrated with multisystem inflammatory syndrome in children.

Scientific reports
Rapid and accurate diagnosis of emerging inflammatory illnesses is challenging due to overlapping clinical features with existing conditions. We demonstrate an approach that integrates proteomic analysis with machine learning to identify diagnostic p...

Artificial intelligence in biology and medicine.

Die Naturwissenschaften
This article explores the role of artificial intelligence (AI) in medicine and biology. Special attention is given to areas of biology such as genomics, proteomics, biotechnology, cell, and synthetic biology. In the field of medicine, the emphasis is...

Lactate/albumin ratio predicts mortality in critically ill COVID-19 patients: a retrospective machine learning study.

Scientific reports
Severe COVID-19 often progresses to critical illness, requiring accurate prognostic biomarkers. Lactate-to-albumin ratio (LAR) has been proposed as a novel indicator to estimate the likelihood of death. Using data from the MIMIC database, this retros...

Enhancing explainability in epidemiological predictions using fuzzy logic integrated with machine and deep learning algorithms.

Scientific reports
Epidemiological data is often analyzed without fully accounting for the uncertainties that are key to understanding the nuances of the dataset. While traditional approaches like the SIR mathematical model provide valuable insights, our study aims to ...

TEMPL: A Template-Based Protein-Ligand Pose Prediction Baseline.

Journal of chemical information and modeling
Pose prediction of ligands to proteins remains a central challenge of structure-based drug design. Although data leakage and generalizability concerns remain, data-driven methods for pose prediction (i.e., based on deep learning and diffusion) now ro...

Machine learning models for the prediction of COVID-19 prognosis in the primary health care setting.

BMC primary care
BACKGROUND: Establishing risk factors associated with severity and prognosis in the early stages of the disease is important to identify patients who need specialized care. Creating new clinical tools to improve health decisions and outcomes in the p...