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Leveraging prior knowledge for protein-protein interaction extraction with memory network.

Database : the journal of biological databases and curation
Automatically extracting protein-protein interactions (PPIs) from biomedical literature provides additional support for precision medicine efforts. This paper proposes a novel memory network-based model (MNM) for PPI extraction, which leverages prior...

Removal of batch effects using distribution-matching residual networks.

Bioinformatics (Oxford, England)
MOTIVATION: Sources of variability in experimentally derived data include measurement error in addition to the physical phenomena of interest. This measurement error is a combination of systematic components, originating from the measuring instrument...

Deep Reinforcement Learning for Dynamic Treatment Regimes on Medical Registry Data.

Healthcare informatics : the business magazine for information and communication systems
In this paper, we propose the first deep reinforcement learning framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces tha...

Discriminating sample groups with multi-way data.

Biostatistics (Oxford, England)
High-dimensional linear classifiers, such as distance weighted discrimination (DWD) and versions of the support vector machine (SVM), are commonly used in biomedical research to distinguish groups of subjects based on a large number of features. Howe...

[Applications of eco-environmental big data: Progress and prospect].

Ying yong sheng tai xue bao = The journal of applied ecology
With the advance of internet and wireless communication technology, the fields of ecology and environment have entered a new digital era with the amount of data growing explosively and big data technologies attracting more and more attention. The eco...

Toward Automating HIV Identification: Machine Learning for Rapid Identification of HIV-Related Social Media Data.

Journal of acquired immune deficiency syndromes (1999)
INTRODUCTION: "Social big data" from technologies such as social media, wearable devices, and online searches continue to grow and can be used as tools for HIV research. Although researchers can uncover patterns and insights associated with HIV trend...

Canonical correlation analysis to identify the semen characteristics used to forecast the freeze survival of Curimba (Prochilodus lineatus) spermatozoa.

Cryo letters
UNLABELLED:   OBJECTIVE: To identify which sperm characteristics were able to predict more accurately the quality of curimba (Prochilodus lineatus) semen upon freezing using canonical correlation analysis.

A Study on Data-Driven Novel Cancer Staging Methods.

Studies in health technology and informatics
This paper presents a data-driven method to study the relationship of survival and clinical information of patients. The machine learning models were established to study the survival situation at the time of interest based on survival analysis. The ...

Making Sense of Patient-Generated Health Data for Interpretable Patient-Centered Care: The Transition from "More" to "Better".

Studies in health technology and informatics
The rise of health consumers and the accumulation of patient-generated health data (PGHD) have brought the patient to the centerstage of precision health and behavioral science. In this positional paper we outline an interpretability-aware framework ...