AIMC Topic: Sulfotransferases

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DCN, NPM3 and SULF1 are hub genes related to vasculogenic mimicry in lung adenocarcinoma.

Journal of cancer research and clinical oncology Nov 8, 2025
AIM: Vasculogenic mimicry (VM), a process in which cancer cells form endothelial cell-independent vascular networks, is a hallmark of tumor aggressiveness in lung adenocarcinoma (LUAD) and supports tumor growth and metastasis. This study aims to iden...
Humans Biomarkers, Tumor Animals Gene Expression Profiling Lung Neoplasms Mice Gene Expression Regulation, Neoplastic Nuclear Proteins Mice, Nude Neovascularization, Pathologic Adenocarcinoma of Lung Nucleophosmin Sulfotransferases
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Integrating Machine Learning and Mendelian Randomization Determined a Functional Neurotrophin-Related Gene Signature in Patients with Lower-Grade Glioma.

Molecular biotechnology Jan 23, 2024
Recent researches reported that neurotrophins can promote glioma growth/invasion but the relevant model for predicting patients' survival in Lower-Grade Gliomas (LGGs) lacked. In this study, we adopted univariate Cox analysis, LASSO regression, and m...
Humans Machine Learning Prognosis Female Brain Neoplasms Male Polymorphism, Single Nucleotide Gene Expression Regulation, Neoplastic Glioma DNA Copy Number Variations Mendelian Randomization Analysis Neoplasm Grading Proportional Hazards Models Homeodomain Proteins Nerve Growth Factors Sulfotransferases
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