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Synthetic Biology

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Synthetic collective intelligence.

Bio Systems
Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human brain, probably co-evolving with...

TensorFlow: Biology's Gateway to Deep Learning?

Cell systems
TensorFlow is Google's recently released open-source software for deep learning. What are its applications for computational biology?

Artificial intelligence and synthetic biology: A tri-temporal contribution.

Bio Systems
Artificial intelligence can make numerous contributions to synthetic biology. I would like to suggest three that are related to the past, present and future of artificial intelligence. From the past, works in biology and artificial systems by Turing ...

Managing bioengineering complexity with AI techniques.

Bio Systems
Our capabilities for systematic design and engineering of biological systems are rapidly increasing. Effectively engineering such systems, however, requires the synthesis of a rapidly expanding and changing complex body of knowledge, protocols, and m...

The role of regulation in the origin and synthetic modelling of minimal cognition.

Bio Systems
In this paper we address the question of minimal cognition by investigating the origin of some crucial cognitive properties from the very basic organisation of biological systems. More specifically, we propose a theoretical model of how a system can ...

[Machine learning-aided design of synthetic biological parts and circuits].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Synthetic biology is an emerging interdisciplinary field at the convergence of biology, engineering, and computer science. It employs a bottom-up approach to progressively design biological parts, devices, and circuits, aiming to create artificial bi...

[Intelligent design of nucleic acid elements in biomanufacturing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Nucleic acid elements are essential functional sequences that play critical roles in regulating gene expression, optimizing pathways, and enabling gene editing to enhance the production of target products in biomanufacturing. Therefore, the design an...

[Artificial intelligence-assisted design, mining, and modification of CRISPR-Cas systems].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
With the rapid advancement of synthetic biology, CRISPR-Cas systems have emerged as a powerful tool for gene editing, demonstrating significant potential in various fields, including medicine, agriculture, and industrial biotechnology. This review co...

[Databases, knowledge bases, and large models for biomanufacturing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Biomanufacturing is an advanced manufacturing method that integrates biology, chemistry, and engineering. It utilizes renewable biomass and biological organisms as production media to scale up the production of target products through fermentation. C...

Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next-generation therapeutics.

Clinical and translational medicine
The eXchange Unit between Thiolation domains approach and artificial intelligence (AI)-driven tools like Synthetic Intelligence are transforming nonribosomal peptide synthetase and polyketide synthase engineering, enabling the creation of novel bioac...