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Indicators and Reagents

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Synthesis and Evaluation of Biological Activities of Aziridine Derivatives of Urea and Thiourea.

Molecules (Basel, Switzerland)
In the present paper, we report the synthesis and evaluation of in vitro antimicrobial activities of aziridine-thiourea derivatives. A series of aziridines in reaction with isocyanates and isothiocyanates to obtain urea and thiourea derivatives were ...

[Research on the Spectrophotometry for Determination of Flavonoids in Waste Residue of Stevia Rebaudiana].

Guang pu xue yu guang pu fen xi = Guang pu
A spectrophotometric method for the determination of flavonoids content in Waste Residue of Stevia Rebaudiana was established by comparing the UV-Vis spectra with three spectrophotometric methods: Direct, AlCl3 and NaNO2-Al (NO3)3-NaOH method. The ef...

Automation of the Differential Digestion Process of Sexual Assault Evidence.

Journal of forensic sciences
Sexual assault evidence samples require the use of a specific process known as a differential digestion to separate sperm from nonsperm cells prior to DNA extraction. An automated differential digestion process was developed using a selective degrada...

Controlling an organic synthesis robot with machine learning to search for new reactivity.

Nature
The discovery of chemical reactions is an inherently unpredictable and time-consuming process. An attractive alternative is to predict reactivity, although relevant approaches, such as computer-aided reaction design, are still in their infancy. React...

[Study on Risk Assessment Model of in Diagnostic Reagent Adverse Events Based on BP Neural Network].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
OBJECTIVE: To modify the monitoring process and means of adverse events diagnostic reagents,improve the quantity and quality of adverse events reported ,and reduce the workload of regulatory authorities,eventually ensure the safety and effectiveness...

Development of a paper-based analytical device for the colourimetric detection of alanine transaminase and the application of deep learning for image analysis.

Analytica chimica acta
A paper-based colourimetric assay for the detection of alanine transaminase has been developed. In the presence of alanine transaminase, 2,4-dinitrophenyl hydrazine changes to pyruvate hydrazone leading to a colour change from pale yellow to dark yel...

Ferrobotic swarms enable accessible and adaptable automated viral testing.

Nature
Expanding our global testing capacity is critical to preventing and containing pandemics. Accordingly, accessible and adaptable automated platforms that in decentralized settings perform nucleic acid amplification tests resource-efficiently are requi...

Active Learning to Select the Most Suitable Reagents and One-Step Organic Chemistry Reactions for Prioritizing Target-Specific Hits from Ultralarge Chemical Spaces.

Journal of chemical information and modeling
Designing chemically novel and synthesizable ligands from the largest possible chemical space is a major issue in modern drug discovery to identify early hits that are easily amenable to medicinal chemistry optimization. Starting from the sole three-...