AIMC Topic: Toll-Like Receptor 9

Clear Filters Showing 1 to 2 of 2 articles

Association of TLR 9 gene polymorphisms with remission in patients with rheumatoid arthritis receiving TNF-α inhibitors and development of machine learning models.

Scientific reports Oct 11, 2021
Toll-like receptor (TLR)-4 and TLR9 are known to play important roles in the immune system, and several studies have shown their association with the development of rheumatoid arthritis (RA) and regulation of tumor necrosis factor alpha (TNF-α). Howe...
Humans Machine Learning Tumor Necrosis Factor-alpha Prognosis Female Aged Aged, 80 and over Young Adult Adult Male Middle Aged Arthritis, Rheumatoid Genetic Predisposition to Disease Polymorphism, Single Nucleotide Genotype Follow-Up Studies Antirheumatic Agents Toll-Like Receptor 9
View on PubMed DOI

Broadly active intranasal influenza vaccine with a nanocomplex particulate adjuvant targeting mast cells and toll-like receptor 9.

Journal of controlled release : official journal of the Controlled Release Society Aug 10, 2025
Flumist is the only FDA-approved intranasal influenza vaccine. Although it has recently been approved for at-home use, it has significant limitations. These include reduced effectiveness in generating a protective immune response in patients with ext...
Humans Female Animals Mice Nanoparticles Mice, Inbred BALB C Mast Cells Adjuvants, Immunologic Influenza Vaccines Orthomyxoviridae Infections Administration, Intranasal Oligodeoxyribonucleotides Hemagglutinin Glycoproteins, Influenza Virus Toll-Like Receptor 9
View on PubMed DOI
Popular Topics
Recent Journals