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Uncertainty

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A review of uncertainty quantification in medical image analysis: Probabilistic and non-probabilistic methods.

Medical image analysis
The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering widespread adop...

Uncertainty estimation and evaluation of deformation image registration based convolutional neural networks.

Physics in medicine and biology
Fast and accurate deformable image registration (DIR), including DIR uncertainty estimation, is essential for safe and reliable clinical deployment. While recent deep learning models have shown promise in predicting DIR with its uncertainty, challeng...

Evaluation of an automated clinical decision system with deep learning dose prediction and NTCP model for prostate cancer proton therapy.

Physics in medicine and biology
To evaluate the feasibility of using a deep learning dose prediction approach to identify patients who could benefit most from proton therapy based on the normal tissue complication probability (NTCP) model.Two 3D UNets were established to predict ph...

Empirical validation of Conformal Prediction for trustworthy skin lesions classification.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly within high-r...

Sliding mode control for uncertain fractional-order reaction-diffusion memristor neural networks with time delays.

Neural networks : the official journal of the International Neural Network Society
This paper investigates a sliding mode control method for a class of uncertain delayed fractional-order reaction-diffusion memristor neural networks. Different from most existing literature on sliding mode control for fractional-order reaction-diffus...

Uncertain prediction of deformable image registration on lung CT using multi-category features and supervised learning.

Medical & biological engineering & computing
The assessment of deformable registration uncertainty is an important task for the safety and reliability of registration methods in clinical applications. However, it is typically done by a manual and time-consuming procedure. We propose a novel aut...

Deep neural network uncertainty estimation for early oral cancer diagnosis.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
BACKGROUND: Early diagnosis in oral cancer is essential to reduce both morbidity and mortality. This study explores the use of uncertainty estimation in deep learning for early oral cancer diagnosis.

Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy.

Physics in medicine and biology
In brachytherapy, deep learning (DL) algorithms have shown the capability of predicting 3D dose volumes. The reliability and accuracy of such methodologies remain under scrutiny for prospective clinical applications. This study aims to establish fast...

Partial label learning for automated classification of single-cell transcriptomic profiles.

PLoS computational biology
Single-cell RNA sequencing (scRNASeq) data plays a major role in advancing our understanding of developmental biology. An important current question is how to classify transcriptomic profiles obtained from scRNASeq experiments into the various cell t...

Semi-Supervised Medical Image Segmentation Using Cross-Style Consistency With Shape-Aware and Local Context Constraints.

IEEE transactions on medical imaging
Despite the remarkable progress in semi-supervised medical image segmentation methods based on deep learning, their application to real-life clinical scenarios still faces considerable challenges. For example, insufficient labeled data often makes it...