AIMC Topic: Unfolded Protein Response

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Deep Visual Proteomics maps proteotoxicity in a genetic liver disease.

Nature
Protein misfolding diseases, including α1-antitrypsin deficiency (AATD), pose substantial health challenges, with their cellular progression still poorly understood. We use spatial proteomics by mass spectrometry and machine learning to map AATD in h...

Glycotherapy: A New Paradigm in Breast Cancer Research.

Biomolecules
Breast cancer is an ancient disease recognized first by the Egyptians as early as 1600 BC. The first cancer-causing gene in a chicken tumor virus was found in 1970. The United States signed the National Cancer Act in 1971, authorizing federal funding...