Novel insights into cardiac contractile dysfunction at the cellular level could deepen understanding of arrhythmia and heart injury, which are leading causes of morbidity and mortality worldwide. We present a comprehensive experimental and computatio...
Animal behavior is adapted to the sensory environment in which it evolved, while also being constrained by physical limits, evolutionary history, and developmental trajectories. The hunting behavior of larval zebrafish (), a cyprinid native to stream...
High-throughput screening for inhibitors of protein-protein interactions (PPIs) provides vital information for therapeutic intervention in diseases driven by aberrant PPIs. Traditionally, the discovery of PPI inhibitors involves sequential steps: in ...
ETHNOPHARMACOLOGICAL RELEVANCE: Angong Niuhuang Pills (AGNHP), a famous Chinese medicine compound preparation, is widely used to treat stroke and other brain disorders. However, owing to the complexity of herbal components and diversity of production...
Revealing the evolved mechanisms that give rise to collective behavior is a central objective in the study of cellular and organismal systems. In addition, understanding the algorithmic basis of social interactions in a causal and quantitative way of...
The zebrafish embryo is a valuable model for evaluating whole effluent toxicity (WET). However, the widely recognized acute toxicity indicator, based on International Organization of Standardization (ISO) methods, requires large numbers of embryos an...
Journal of agricultural and food chemistry
Apr 16, 2025
Aquaculture is a rapidly growing sector of global food production, playing a vital role in poverty alleviation, food security, and income generation. However, it faces substantial challenges, particularly due to infections caused by the protozoan , l...
Organophosphorus flame retardants (OPFRs) are important chemical additives that are used in commercial products. However, owing to increasing health concerns, the discovery of new OPFRs has become imperative. Herein, we propose an explainable artific...
The androgen receptor (AR) activation by androgens is vital for tissue development, sexual differentiation, and reproductive attributes in zebrafish (). However, our understanding of the molecular mechanisms behind their activation remains limited. I...
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