AI Medical Compendium

Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation Aug 19, 2025

BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)... read more

Humans Brain Female Aged Adult Cross-Sectional Studies Male Aging Middle Aged Longitudinal Studies Magnetic Resonance Imaging Multiple Sclerosis White Matter

A Molecular Descriptor for Characterizing the Strength of Through-Space Conjugation for Luminescent Property in Organic Materials.

The journal of physical chemistry letters Aug 19, 2025

Noncovalent through-space conjugation (TSC), a unique property of π-charge delocalization, has emerged as a powerful strategy for modulating the optoelectronic properties of organic materials. However, the quantitative relationship among the molecula... read more

Machine Learning Integrating Surface Features and Crystal Similarity for Exploring 2D Materials.

The journal of physical chemistry letters Aug 19, 2025

The property prediction of two-dimensional (2D) materials has been constrained to specific systems or the highly self-similar Computational 2D Materials Database (C2DB) due to limited data availability and inadequate feature extraction. These challen... read more

Accelerating the Pace of Oxygen Evolution Reaction Catalyst Discovery through Megalibraries.

Journal of the American Chemical Society Aug 19, 2025

Iridium (Ir) catalysts are essential for the acidic oxygen evolution reaction (OER) in proton-exchange membrane water electrolyzers (PEMWEs), but their high cost, scarcity, and geographical concentration limit large-scale adoption. In addition, the d... read more

Efficient neural encoding as revealed by bilingualism.

Proceedings of the National Academy of Sciences of the United States of America Aug 19, 2025

The remarkable human capacity for bilingual and multilingual acquisition raises fundamental questions about how the brain develops efficient systems for processing multiple languages. In this study, we used neural network models trained on natural sp... read more

Humans Neural Networks, Computer Brain Language Learning Speech Models, Neurological Multilingualism Language Development

Sparse autoencoders uncover biologically interpretable features in protein language model representations.

Proceedings of the National Academy of Sciences of the United States of America Aug 19, 2025

Foundation models in biology-particularly protein language models (PLMs)-have enabled ground-breaking predictions in protein structure, function, and beyond. However, the "black-box" nature of these representations limits transparency and explainabil... read more

Humans Computational Biology Proteins Natural Language Processing Gene Ontology Autoencoder

Acceptance of AI-Powered Chatbots Among Physiotherapy Students: International Cross-Sectional Study.

JMIR medical education Aug 19, 2025

BACKGROUND: Artificial intelligence-powered chatbots (AI-PCs) are increasingly integrated into educational settings, including health care disciplines. Despite their potential to enhance learning, limited research has investigated physiotherapy (PT) ... read more

Humans Artificial Intelligence Female Young Adult Adult Cross-Sectional Studies Male Students Surveys and Questionnaires Generative Artificial Intelligence Physical Therapy Specialty Students, Health Occupations

Rethinking anticholinergic burden in older adults: innovative approaches to detection and management.

Expert review of clinical pharmacology Aug 19, 2025

INTRODUCTION: Anticholinergic burden (AChB), the cumulative impact of medications with anticholinergic properties, is a modifiable risk factor linked to cognitive impairment, falls, and functional decline in older adults. Yet despite the availability... read more

Microfluidics for geosciences: metrological developments and future challenges.

Lab on a chip Aug 19, 2025

This review addresses the main metrological developments over the past decade for microfluidics applied to geosciences. Microfluidic experiments for geosciences seek to decipher the complex interplay between coupled, multiphase, and reactive processe... read more

Regulation of biomarker analysis: what can be translated in the clinic?

Expert review of molecular diagnostics Aug 19, 2025

INTRODUCTION: The introduction of biomarkers in precision medicine is heralding a new era of diagnostic power and personalized patient care. Biomarkers are critical tools for detecting various diseases, guiding treatment decisions, and predicting pat... read more

Artificial Intelligence Medical Compendium