European journal of clinical pharmacology
Jan 19, 2026
PURPOSE: The primary purpose of this study is to systematically evaluate how accurately artificial intelligence (AI) models can predict optimal warfarin dosing by incorporating both genetic variations-particularly in VKORC1 and CYP2C9-and clinical pa... read more
Tauopathies are characterised by a progressive accumulation of hyperphosphorylated tau. However, early and intermediate stages remain challenging to quantify due to subtle and heterogeneous morphological characteristics. This study evaluates a deep l... read more
The transition from laparoscopic to robotic surgery for left-sided colorectal cancer raises safety concerns during the learning curve, particularly when complex cases are preferentially selected for the robotic platform. We evaluated a machine learni... read more
Journal of molecular neuroscience : MN
Jan 19, 2026
Huntington's disease (HD) is a rare, inherited neurodegenerative disorder caused by the expanded CAG repeats in the huntingtin gene. The HD domain still lacks detailed knowledge of validated drug targets, limiting the effectiveness of classical metho... read more
Physical and engineering sciences in medicine
Jan 19, 2026
The role of adipose tissue in predicting microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) remains unclear. This study proposes a method that integrates deep learning and machine learning techniques to investigate the role ... read more
Percutaneous puncture techniques have been widely adopted across various domains of modern clinical interventional therapy due to their high diagnostic specificity, minimal invasiveness, and rapid postoperative recovery. However, the nonholonomic kin... read more
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Jan 19, 2026
Amyloid fibrils formed by the misfolding and aggregation of proteins are a pathological hallmark of many neurodegenerative conditions including Alzheimer's disease (AD). Although recent studies have shown that pre-fibrillar species including low mole... read more
Environmental science and pollution research international
Jan 19, 2026
Climate change is a critical global challenge driven by rising greenhouse gas emissions, particularly carbon dioxide CO 2 . Accurate forecasting of CO 2 emissions is essential for developing effective mitigation strategies. This study focuses o... read more
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