Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 361-380 of 6,921 articles

Food safety assessment of hemipteran-specific insecticidal protein Tpp78Aa from Bacillus thuringiensis.

BACKGROUND: Hemipteran pests pose a significant threat to global agriculture, creating a continuous need for effective and safe control strategies. Tpp78Aa, a distinctive Bacillus thuringiensis (Bt) insecticidal protein, represents a breakthrough as the first single-component Bt protein with high efficacy against these challenging hemipteran pests. Before its application in transgenic crops, a com...

Apr 15 2026 41986881

[Comparative observation of analgesic efficacy between liposomal bupivacaine and "cocktail" therapy following artificial intelligence-assisted direct anterior approach total hip arthroplasty: A prospective randomized controlled study].

OBJECTIVE: To compare the analgesic efficacy and safety of liposomal bupivacaine (LB) versus ropivacaine for surgical incision local anesthesia after artificial intelligence (AI)-assisted direct anterior approach (DAA) total hip arthroplasty (THA). METHODS: A prospective randomized controlled study was conducted. A total of 120 patients who underwent AI-assisted DAA-THA between March 2024 and Janu...

Apr 15 2026 41981425
Bioinformatics analysis and qRT-PCR validation of iron metabolism-related genes in pediatric asthma.

Pediatric asthma (PA) is a chronic airway disease with a complex etiology, and iron metabolism disorder is believed to be involved in its pathogenesis...

Apr 15 2026 41984875
STC2-mediated calcium homeostasis dysregulation in the osteosarcoma microenvironment: Insights from single-cell sequencing and machine learning.

BACKGROUND: Osteosarcoma (OS) is an aggressive bone malignancy with a poor prognosis. Dysregulated calcium homeostasis may contribute to OS progressio...

Apr 14 2026 41985319
Cross-task interpretability through unified modeling reveals a universal shortcut bias in neoantigen prediction.

Accurate neoantigen prediction is central to the design of personalized cancer immunotherapy. The immune recognition of neoantigens is a multi-step pr...

Apr 14 2026 41985452
Imaging Immune Heterogeneity in Nasopharyngeal Carcinoma: A Multidimensional Radiomics Perspective.

RATIONALE AND OBJECTIVES: Nasopharyngeal carcinoma (NPC) is characterized by a distinctive virologic and immunologic profile, in which Epstein-Barr vi...

Apr 14 2026 41986218
Comparison of AI-based Chatbot Performance in Analyzing Clinical Scenarios versus Medical Residents: A Novel Approach in Chest Diseases Education.

OBJECTIVE: Rapid advancements in artificial intelligence (AI) technologies offer new opportunities in medical education. The aim of this study is to c...

Apr 14 2026 41979097
A global perspective on autoimmunity and immunodeficiency: exploring geoepidemiology trends.

Autoimmune and primary immunodeficiency disorders represent a growing global health burden influenced by a complex interplay of genetic, environmental...

Apr 13 2026 41980333
Personalized neoantigen cancer vaccines: Why clinical benefit remains inconsistent.

Personalized cancer vaccines have re-emerged as a promising strategy in precision immunotherapy, driven by advances in tumor sequencing, neoantigen id...

Apr 12 2026 41974392
[Expert consensus on optimizing the multidisciplinary clinical pathways and management models for pulmonary function testing].

The promotion and application of pulmonary function tests (PFTs) in China have achieved preliminary success;however, numerous deficiencies persist in ...

Apr 12 2026 41912385
Regulatory B cells and SIVA1-LAG3 immune suppression predict poor prognosis in prostate cancer.

Prostate cancer (PCa) is among the most prevalent malignancies affecting men globally. The immunosuppressive characteristics of the tumor microenviron...

Apr 10 2026 41960835
Artificial Intelligence in Asthma: From Diagnosis to Management.

Artificial intelligence (AI) offers new opportunities to improve asthma management across the care process. This review synthesizes evidence on AI app...

Apr 10 2026 41960858
Deep learning-based pathomics signature predicts prognosis and treatment response in gastric cancer: a multicenter retrospective study.

The existing TNM staging system provides insufficient prognostic information in gastric cancer (GC) patients. This study aims to establish a pathomics...

Apr 10 2026 41957258
Multimodal large language models for food safety detection within deep learning frameworks: a review.

As the food industry continues to evolves and global trade expands, food safety challenges have become increasingly diverse, concealed, and frequent. ...

Apr 9 2026 41974072
Efferocytosis-related biomarkers and immune infiltration in pancreatic ductal adenocarcinoma based on single-cell sequencing and machine learning: a comprehensive bioinformatics analysis and experimental validation.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive and lethal malignancy, with its complex tumor microenvironment (TME) severely...

Apr 9 2026 41966742
Targeting cholesterol metabolism: a core regulator of tumor-associated macrophage plasticity and immunotherapy response.

Tumor-associated macrophages (TAMs) are one of the main immunosuppressive components in the tumor microenvironment (TME). Growing evidence indicates t...

Apr 8 2026 41962811
Machine learning-based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer.

Breast cancer (BRCA) heterogeneity necessitates robust prognostic biomarkers. Programmed cell death (PCD) serves a key role in tumor progression and t...

Apr 8 2026 42027644
Targeting immunosenescence in lung diseases: mechanistic insights and clinical interventions.

Immunosenescence, the age-related decline in immune function, plays a crucial role in the pathogenesis and progression of lung diseases, including chr...

Apr 8 2026 41952158
Unsupervised clustering of clinical and laboratory features of systemic lupus erythematosus: insights from a multicentre cohort.

OBJECTIVE: This study explored the relationship between clinical phenotypes and immuno-molecular features of systemic lupus erythematosus (SLE) using ...

Apr 8 2026 41951250
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