Allergy & Immunology

[Comparative observation of analgesic efficacy between liposomal bupivacaine and "cocktail" therapy following artificial intelligence-assisted direct anterior approach total hip arthroplasty: A prospective randomized controlled study].

OBJECTIVE: To compare the analgesic efficacy and safety of liposomal bupivacaine (LB) versus ropivac...

Bioinformatics analysis and qRT-PCR validation of iron metabolism-related genes in pediatric asthma.

Pediatric asthma (PA) is a chronic airway disease with a complex etiology, and iron metabolism disor...

STC2-mediated calcium homeostasis dysregulation in the osteosarcoma microenvironment: Insights from single-cell sequencing and machine learning.

BACKGROUND: Osteosarcoma (OS) is an aggressive bone malignancy with a poor prognosis. Dysregulated c...

Cross-task interpretability through unified modeling reveals a universal shortcut bias in neoantigen prediction.

Accurate neoantigen prediction is central to the design of personalized cancer immunotherapy. The im...

Imaging Immune Heterogeneity in Nasopharyngeal Carcinoma: A Multidimensional Radiomics Perspective.

RATIONALE AND OBJECTIVES: Nasopharyngeal carcinoma (NPC) is characterized by a distinctive virologic...

Comparison of AI-based Chatbot Performance in Analyzing Clinical Scenarios versus Medical Residents: A Novel Approach in Chest Diseases Education.

OBJECTIVE: Rapid advancements in artificial intelligence (AI) technologies offer new opportunities i...

Elucidating the Role of Oxidative Stress-Associated Genes FKBP Prolyl Isomerase 5 in Osteoarthritis Development and Immunological Milieu.

A global perspective on autoimmunity and immunodeficiency: exploring geoepidemiology trends.

Autoimmune and primary immunodeficiency disorders represent a growing global health burden influence...

[Expert consensus on optimizing the multidisciplinary clinical pathways and management models for pulmonary function testing].

The promotion and application of pulmonary function tests (PFTs) in China have achieved preliminary ...

Artificial Intelligence in Asthma: From Diagnosis to Management.

Artificial intelligence (AI) offers new opportunities to improve asthma management across the care p...

Deep learning-based pathomics signature predicts prognosis and treatment response in gastric cancer: a multicenter retrospective study.

The existing TNM staging system provides insufficient prognostic information in gastric cancer (GC) ...

Multimodal large language models for food safety detection within deep learning frameworks: a review.

As the food industry continues to evolves and global trade expands, food safety challenges have beco...

Efferocytosis-related biomarkers and immune infiltration in pancreatic ductal adenocarcinoma based on single-cell sequencing and machine learning: a comprehensive bioinformatics analysis and experimental validation.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive and lethal malignancy, with...

Targeting cholesterol metabolism: a core regulator of tumor-associated macrophage plasticity and immunotherapy response.

Tumor-associated macrophages (TAMs) are one of the main immunosuppressive components in the tumor mi...

Machine learning-based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer.

Breast cancer (BRCA) heterogeneity necessitates robust prognostic biomarkers. Programmed cell death ...

Targeting immunosenescence in lung diseases: mechanistic insights and clinical interventions.

Immunosenescence, the age-related decline in immune function, plays a crucial role in the pathogenes...

Unsupervised clustering of clinical and laboratory features of systemic lupus erythematosus: insights from a multicentre cohort.

OBJECTIVE: This study explored the relationship between clinical phenotypes and immuno-molecular fea...

Microfluidic innovations driving the future of sperm motility and sex sorting techniques.

Sperm sorting plays a pivotal role in assisted reproductive technologies (ART), ensuring the selecti...

Exploring AI and ML in managing overlap between cardiovascular disease and asthma or COPD: a scoping review.

Cardiovascular disease (CVD) is a major comorbidity in asthma and chronic obstructive pulmonary dise...

Integration of multi-omics and machine learning to identify core genes in PANoptosisof lung adenocarcinoma and their mechanisms in the tumor microenvironment and therapeutic potential.

Lung adenocarcinoma (LUAD) is one of the leading causes of cancer-related deaths worldwide, and its ...

Integrative multi-omics identifies a diagnostic T cell signature for cutaneous squamous cell carcinoma.

Cutaneous squamous cell carcinoma (cSCC) involves complex immune interactions. This study aimed to i...