Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Aging-related markers in rat urine revealed by dynamic metabolic profiling using machine learning.

The process of aging and metabolism is intimately intertwined; thus, developing biomarkers related to metabolism is critical for delaying aging. However, few studies have identified reliable markers that reflect aging trajectories based on machine learning. We generated metabolomic profiles from rat urine using ultra-performance liquid chromatography/mass spectrometry. This was dynamically collect...

May 19 2021 34016789

Deep Learning Methods for Improving Pollen Monitoring.

The risk of pollen-induced allergies can be determined and predicted based on data derived from pollen monitoring. Hirst-type samplers are sensors that allow airborne pollen grains to be detected and their number to be determined. Airborne pollen grains are deposited on adhesive-coated tape, and slides are then prepared, which require further analysis by specialized personnel. Deep learning can be...

May 19 2021 34069411
Deep learning for predicting COVID-19 malignant progression.

As COVID-19 is highly infectious, many patients can simultaneously flood into hospitals for diagnosis and treatment, which has greatly challenged publ...

May 12 2021 34051438
Conjunctival Provocation Test With .

Conjunctival provocation test (CPT) is used to demonstrate clinical relevance to a specific allergen. (Bt) is a prevalent allergen in tropical regio...

May 7 2021 35386969
DeepNetBim: deep learning model for predicting HLA-epitope interactions based on network analysis by harnessing binding and immunogenicity information.

BACKGROUND: Epitope prediction is a useful approach in cancer immunology and immunotherapy. Many computational methods, including machine learning and...

May 5 2021 33952199
Network of gold conjugates for enhanced sensitive immunochromatographic assays of troponins.

Highly sensitive detection of cardiac troponins I and T (cTnI and cTnT) was completed by immunochromatography with double amplification, through the b...

May 4 2021 35479181
Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning.

A key hurdle to making adeno-associated virus (AAV) capsid mediated gene therapy broadly beneficial to all patients is overcoming pre-existing and the...

Apr 27 2021 33986759
Opportunities and Challenges in Democratizing Immunology Datasets.

The field of immunology is rapidly progressing toward a systems-level understanding of immunity to tackle complex infectious diseases, autoimmune cond...

Apr 16 2021 33936065
Prioritizing Molecular Biomarkers in Asthma and Respiratory Allergy Using Systems Biology.

Highly prevalent respiratory diseases such as asthma and allergy remain a pressing health challenge. Currently, there is an unmet need for precise dia...

Apr 15 2021 33936056
Analysis of Tumor Microenvironment Characteristics in Bladder Cancer: Implications for Immune Checkpoint Inhibitor Therapy.

The tumor microenvironment (TME) plays a crucial role in cancer progression and recent evidence has clarified its clinical significance in predicting ...

Apr 15 2021 33936117
Applications of Machine and Deep Learning in Adaptive Immunity.

Adaptive immunity is mediated by lymphocyte B and T cells, which respectively express a vast and diverse repertoire of B cell and T cell receptors and...

Apr 14 2021 33852352
A Multimodality Machine Learning Approach to Differentiate Severe and Nonsevere COVID-19: Model Development and Validation.

BACKGROUND: Effectively and efficiently diagnosing patients who have COVID-19 with the accurate clinical type of the disease is essential to achieve o...

Apr 7 2021 33714935
Identification of pediatric respiratory diseases using a fine-grained diagnosis system.

Respiratory diseases, including asthma, bronchitis, pneumonia, and upper respiratory tract infection (RTI), are among the most common diseases in clin...

Apr 6 2021 33831537
Using Deep Learning in a Monocentric Study to Characterize Maternal Immune Environment for Predicting Pregnancy Outcomes in the Recurrent Reproductive Failure Patients.

Recurrent reproductive failure (RRF), such as recurrent pregnancy loss and repeated implantation failure, is characterized by complex etiologies and p...

Apr 1 2021 33868275
Classification and Design of HIV-1 Integrase Inhibitors Based on Machine Learning.

A key enzyme in human immunodeficiency virus type 1 (HIV-1) life cycle, integrase (IN) aids the integration of viral DNA into the host DNA, which has ...

Apr 1 2021 33868450
Characterizing the function of domain linkers in regulating the dynamics of multi-domain fusion proteins by microsecond molecular dynamics simulations and artificial intelligence.

Multi-domain proteins are not only formed through natural evolution but can also be generated by recombinant DNA technology. Because many fusion prote...

Mar 27 2021 33620752
Machine learning analysis of pregnancy data enables early identification of a subpopulation of newborns with ASD.

To identify newborns at risk of developing ASD and to detect ASD biomarkers early after birth, we compared retrospectively ultrasound and biological m...

Mar 25 2021 33767300
Investigating heterogeneities of live mesenchymal stromal cells using AI-based label-free imaging.

Mesenchymal stromal cells (MSCs) are multipotent cells that have great potential for regenerative medicine, tissue repair, and immunotherapy. Unfortun...

Mar 24 2021 33762607
Deep learning approach to skin layers segmentation in inflammatory dermatoses.

Monitoring skin layers with medical imaging is critical to diagnosing and treating patients with chronic inflammatory skin diseases. The high-frequenc...

Mar 21 2021 33784575
Host-dependent molecular factors mediating SARS-CoV-2 infection to gain clinical insights for developing effective targeted therapy.

Coronavirus disease 2019 (COVID-19), a recent viral pandemic that first began in December 2019, in Hunan wildlife market, Wuhan, China. The infection ...

Mar 20 2021 33743061
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