Allergy & Immunology

Latest AI and machine learning research in allergy & immunology for healthcare professionals.

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Showing 2059-2079 of 6,619 articles
Structure-Based TCR-pMHC Binding Prediction and Generalization to Unseen Peptides

The interaction between T-cell receptors (TCRs) with the peptide-bound major histocompatibility comp...

Reproducible symptom subtypes of depression identified using unsupervised machine learning

Depression is a heterogeneous disorder, often diagnosed based on symptom co-occurrence. However, ind...

Generative AI Guided Design of High-Affinity T cell Receptors

Developing T cell receptors (TCRs) with sufficiently high affinity for tumor antigens (TAs) remains ...

EVA: Towards a universal model of the immune system

The effective application of foundation models to translational research in immune-mediated diseases...

Single center Automated, Multi-Source deeply Phenotyped Heart Transplant Registry as a template to build tailored data infrastructure

Background: Traditional heart transplant registries often lack the granularity required for deep phe...

Pathwise Test-Time Correction for Autoregressive Long Video Generation

Distilled autoregressive diffusion models facilitate real-time short video synthesis but suffer from...

Computational Convergence of Adaptive Immunity and Artificial Intelligence

The adaptive immune system and modern artificial intelligence (AI) have independently converged on i...

Selective Glucocorticoid Receptor Modulators of Immune Checkpoint Function

Glucocorticoids (GCs) coordinate immunity, inflammation and metabolism through allosteric regulation...

Ophiuchus-Ab: A Versatile Generative Foundation Model for Advanced Antibody-Based Immunotherapy

Antibodies exhibit extraordinary specificity and diversity in antigen recognition and have become a ...

Data Augmentation for High-Fidelity Generation of CAR-T/NK Immunological Synapse Images

Chimeric antigen receptor (CAR)-T and NK cell immunotherapies have transformed cancer treatment, and...

AI quantification of inflammatory and architectural features in ulcerative colitis distinguishes active disease from remission

Background and Aims: Artificial intelligence (AI) is increasingly applied to histological assessment...

Persistent Proxy Discrimination in HIV Testing Prediction Models: A National Fairness Audit of 386,775 US Adults

Background: Human immunodeficiency virus (HIV) disproportionately affects marginalized communities i...

Structure-constrained Language-informed Diffusion Model for Unpaired Low-dose Computed Tomography Angiography Reconstruction

The application of iodinated contrast media (ICM) improves the sensitivity and specificity of comput...

TCRAD: An End-to-End Framework for Antigen-Targeted T Cell Receptor Design

Understanding and engineering T-cell receptor (TCR) specificity is central to personalized immunothe...

Reprogramming BCMA-Targeted CAR-T Cells through γ-Secretase Modulation Blocks Antigen Shedding and Extends CAR-T Longevity

B-cell maturation antigen (BCMA) shedding by {gamma}-secretase generates soluble BCMA (sBCMA) , whic...

I3LUNG: Clinical Validation of a Multimodal AI Tool to Support Immunotherapy Decisions in NSCLC

Despite a decade of immunotherapy, treatment selection in non-small cell lung cancer (NSCLC) still r...

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