Latest AI and machine learning research in allergy for healthcare professionals.
Background Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the progressive deterioration of articular cartilage, significantly impacting the quality of life in middle-aged and elderly populations. The Ras and Hippo signaling pathways play critical roles in regulating cell proliferation, differentiation, and stress responses; however, their interactive mechanisms in OA ...
Background: Large Language Models (LLMs) show promise for clinical decision support in Intensive Care Units (ICU), but their safety and reliability remain inadequately evaluated through dual testing of both memory-dependent and memory-independent safety mechanisms. Objective: To comprehensively evaluate LLMs using two independent safety tests: context-dependent contraindication memory (penicillin ...
Distilled autoregressive diffusion models facilitate real-time short video synthesis but suffer from severe error accumulation during long-sequence ge...
Glucocorticoids (GCs) coordinate immunity, inflammation and metabolism through allosteric regulation of the glucocorticoid receptor (GR) transcription...
Antibodies exhibit extraordinary specificity and diversity in antigen recognition and have become a central class of therapeutics across a wide range ...
Chimeric antigen receptor (CAR)-T and NK cell immunotherapies have transformed cancer treatment, and recent studies suggest that the quality of the CA...
Background and Aims: Artificial intelligence (AI) is increasingly applied to histological assessment in inflammatory bowel disease (IBD), but most app...
The application of iodinated contrast media (ICM) improves the sensitivity and specificity of computed tomography (CT) for a wide range of clinical in...
Understanding and engineering T-cell receptor (TCR) specificity is central to personalized immunotherapy and antigen discovery. However, while antigen...
B-cell maturation antigen (BCMA) shedding by {gamma}-secretase generates soluble BCMA (sBCMA) , which diminishes membrane antigen density, and limits ...
Despite a decade of immunotherapy, treatment selection in non-small cell lung cancer (NSCLC) still relies on subgroup analyses and clinical scores. I3...
Understanding the role of tertiary lymphoid structures (TLS) is crucial in non-small cell lung cancer (NSCLC), as they are associated with patient pro...
AI agents promise to empower biomedical discovery, but realizing this promise requires the ability to complete transparent, long-horizon analyses usin...
Reconstructing realistic animal fur geometry from images is a challenging task due to the fine-scale details, self-occlusion, and view-dependent appea...
Background/ObjectivesHead and neck cancer (HNC) represents the seventh most common cancer diagnosis globally, yet current treatments, including surger...
Azelastine hydrochloride (AZE) and Mometasone furoate (MOM) combination is used to treat allergic rhinitis' symptoms. The aim of this work is to quali...
Tumoral PD-L1 expression is assessed to weigh immunotherapy options in the treatment of various types of cancer. To determine PD-L1 expression, each t...
The direction of anticancer therapies has changed in recent years, including the increasing use of immunotherapy. However, around 50 % of non-small-ce...
Leveraging the powerful representations of pre-trained vision foundation models -- traditionally used for visual comprehension -- we explore a novel...
Pain is an inherent part of human existence, manifesting as both physical and emotional experiences, and can be categorized as either acute or chron...