Latest AI and machine learning research in allergy & immunology for healthcare professionals.
Despite advancements in therapeutic cancer vaccines, clinical translation has been hindered by limited efficacy, with Sipuleucel-T remaining the only FDA-approved therapeutic cancer vaccine to date. However, recent advances in personalized mRNA vaccines, such as Moderna's mRNA-4157 and BioNTech's autogene cevumeran, have demonstrated significant reductions in recurrence risk and improved survival ...
OBJECTIVE: This study constructed a predictive model for interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) and explored the value of interpretable machine learning. METHODS: The medical records of 400 hospitalized RA patients treated in the Department of Rheumatology and Immunology, the First Affiliated Hospital of Anhui University of Chinese Medicine, from July 2021 to Ja...
OBJECTIVE: Automating administrative tasks, such as compiling a patient's medical history, could help general practitioners in their daily work. AI pe...
Immunotherapy has revolutionized the treatment landscape of breast cancer, particularly for triple-negative breast cancer (TNBC), yet primary and acqu...
The proposed work aims to develop a compact, low-cost, and commercially viable microwave sensor for early monitoring of high protein content in blood,...
BACKGROUND: EphrinB2 and its receptor EphB4 have been reported to play a crucial role in the development of the cardiovascular system, and the process...
Mechanisms of neurotransmitter detection using a two-dimensional MoS2 platform are discussed. Machine learning methods are applied to distinguish the ...
Postoperative erectile dysfunction remains a highly debilitating complication following robot assisted radical prostatectomy for localized prostate ca...
BACKGROUND: Multiple programmed cell death (PCD) modalities, including apoptosis, autophagy, and ferroptosis, are closely implicated in spontaneous pr...
Cow's milk-specific IgE (sIgE) is a crucial serum biomarker for cow's milk allergy (CMA) in children. However, its low abundance and the scarcity of r...
Despite remarkable achievements in infectious disease control, more than 20 major pathogens responsible for significant global morbidity and mortality...
Cardiogenic shock (CS) patients receiving extracorporeal membrane oxygenation (ECMO) exhibit profound immune and metabolic disturbances, which may inf...
BACKGROUND: Coronary artery lesions (CAL) complicating Kawasaki disease (KD) are a central concern affecting the long-term cardiovascular health of af...
Over the past three decades, adenosine signalling has emerged as a fundamental regulatory system controlling immune responses, tissue homeostasis, met...
BACKGROUND: Hypersensitivity pneumonitis (HP) manifests as fibrotic (FHP) and non-fibrotic (NFHP) phenotypes. Clinically distinguishing FHP from idiop...
BACKGROUND: Postoperative pulmonary infection (PPI) is a common and serious complication in older adults undergoing hip fracture surgery, leading to p...
Cancer vaccines are an attractive immunotherapeutic approach, and numerous clinical trials are ongoing. However, most candidates have not achieved sta...
This study aimed to develop and validate an interpretable machine learning (ML) model using routine laboratory data to support clinical decision-makin...
The ability to predict T-cell receptor (TCR) specificity from sequences could transform immunotherapy, vaccine development, and our understanding of i...
Although diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, existing prognostic tools, including the revised International Prognostic I...