Geriatrics

Alzheimer's Disease

Latest AI and machine learning research in alzheimer's disease for healthcare professionals.

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Geriatrics Subcategories: Alzheimer's Disease Medicare
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Targeting C99 Mediated Metabolic Disruptions with Ketone Therapy in Alzheimer's Disease

The role of ketone bodies in Alzheimers disease (AD) remains incompletely understood, particularly regarding their influence on amyloid pathology. While beta}hydroxybutyrate (BHB) has been implicated in neuroprotection, direct evidence for its effects on amyloid beta(Abeta) deposition, aggregation, or clearance is lacking. Furthermore, whether BHB acts as a disease modifying factor or merely con...

Developing Conversational Speech Systems for Robots to Detect Speech Biomarkers of Cognition in People Living with Dementia

This study presents the development and testing of a conversational speech system designed for robots to detect speech biomarkers indicative of cognitive impairments in people living with dementia (PLwD). The system integrates a backend Python WebSocket server and a central core module with a large language model (LLM) fine-tuned for dementia to process user input and generate robotic conversati...

NeuroXVocal: Detection and Explanation of Alzheimer's Disease through Non-invasive Analysis of Picture-prompted Speech

The early diagnosis of Alzheimer's Disease (AD) through non invasive methods remains a significant healthcare challenge. We present NeuroXVocal, a n...

Analyzing Patient Daily Movement Behavior Dynamics Using Two-Stage Encoding Model

In the analysis of remote healthcare monitoring data, time series representation learning offers substantial value in uncovering deeper patterns of ...

Evaluating GPT's Capability in Identifying Stages of Cognitive Impairment from Electronic Health Data

Identifying cognitive impairment within electronic health records (EHRs) is crucial not only for timely diagnoses but also for facilitating research...

Lifespan tree of brain anatomy: diagnostic values for motor and cognitive neurodegenerative diseases

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with arti...

Two-Stage Representation Learning for Analyzing Movement Behavior Dynamics in People Living with Dementia

In remote healthcare monitoring, time series representation learning reveals critical patient behavior patterns from high-frequency data. This study...

Choroidal image analysis for OCT image sequences with applications in systemic health

The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with ...

Can ChatGPT Diagnose Alzheimer's Disease?

Can ChatGPT diagnose Alzheimer's Disease (AD)? AD is a devastating neurodegenerative condition that affects approximately 1 in 9 individuals aged 65...

Image-Based Alzheimer's Disease Detection Using Pretrained Convolutional Neural Network Models

Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their ...

Explainable and externally validated machine learning for neuropsychiatric diagnosis via electrocardiograms

Electrocardiogram (ECG) analysis has emerged as a promising tool for identifying physiological changes associated with neuropsychiatric conditions. ...

DECT: Harnessing LLM-assisted Fine-Grained Linguistic Knowledge and Label-Switched and Label-Preserved Data Generation for Diagnosis of Alzheimer's Disease

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of ke...

Leveraging Geolocation in Clinical Records to Improve Alzheimer's Disease Diagnosis Using DMV Framework

Alzheimer's Disease (AD) early detection is critical for enabling timely intervention and improving patient outcomes. This paper presents a DMV fram...

Unravelling Causal Genetic Biomarkers of Alzheimer's Disease via Neuron to Gene-token Backtracking in Neural Architecture: A Groundbreaking Reverse-Gene-Finder Approach

Alzheimer's Disease (AD) affects over 55 million people globally, yet the key genetic contributors remain poorly understood. Leveraging recent advan...

Diagnosis of Alzheimer's disease using FusionNet with improved secretary bird optimization algorithm for optimal MK-SVM based on imaging genetic data.

Alzheimer's disease is an irreversible central neurodegenerative disease, and early diagnosis of Alzheimer's disease is beneficial for its prevention ...

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Dementia Classification Using Acoustic Speech and Feature Selection

Dementia is a general term for a group of syndromes that affect cognitive functions such as memory, thinking, reasoning, and the ability to perform ...

scBIT: Integrating Single-cell Transcriptomic Data into fMRI-based Prediction for Alzheimer's Disease Diagnosis

Functional MRI (fMRI) and single-cell transcriptomics are pivotal in Alzheimer's disease (AD) research, each providing unique insights into neural f...

VisTA: Vision-Text Alignment Model with Contrastive Learning using Multimodal Data for Evidence-Driven, Reliable, and Explainable Alzheimer's Disease Diagnosis

Objective: Assessing Alzheimer's disease (AD) using high-dimensional radiology images is clinically important but challenging. Although Artificial I...

BrainOOD: Out-of-distribution Generalizable Brain Network Analysis

In neuroscience, identifying distinct patterns linked to neurological disorders, such as Alzheimer's and Autism, is critical for early diagnosis and...

Fast Solvers for Discrete Diffusion Models: Theory and Applications of High-Order Algorithms

Discrete diffusion models have emerged as a powerful generative modeling framework for discrete data with successful applications spanning from text...

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