Latest AI and machine learning research in anemia for healthcare professionals.
Chronic pain is a multifaceted condition shaped by biological, psychological, and social factors, which challenges its diagnosis and treatment. While prior research largely focused on sensory profiles to distinguish pain mechanisms, this study adopted a biopsychosocial perspective with the key addition of experimental pain paradigms to identify factors explaining variance in chronic pain severity ...
Cyclosporine A (CsA) functions as a calcineurin inhibitor that perturbs T cell activation via calcineurin-nuclear factor of activated T cells (CaN-NFAT) signaling inhibitors, establishing its central role in hematological therapeutics. This review delineates the contemporary applications and mechanistic underpinnings of CsA across acquired bone marrow failure syndromes spanning severe and non-seve...
BACKGROUND: Serum ferritin is a primary marker of body iron stores; however, its diagnostic utility is limited by cost and non-specific elevation duri...
INTRODUCTION: Healthcare professionals working in busy hospital environments are expected to make multiple back-to-back critical decisions related to ...
Adverse events (AEs) of small molecule kinase inhibitors (SMKIs) at therapeutic doses in cancer patients are largely unpredictable in phase I-III stud...
Excessive fatigue may cause secondary damage to the body during muscle rehabilitation. Therefore, muscle fatigue detection is essential for ensuring t...
BACKGROUND: Kinesin family member 23 (KIF23) is a microtubule-dependent motor protein essential for cytokinesis, organelle transport, and signaling pa...
BACKGROUND: Electroencephalogram (EEG) microstates effectively characterise cognitive-related brain networks, and metal homeostasis is crucial for mai...
Metabolic reprogramming toward aerobic glycolysis, a phenomenon analogous to the Warburg effect, is increasingly recognized as a hallmark of pulmonary...
Children with beta-thalassemia major (β-TM) are at risk of neurodevelopmental or cognitive impairment. In this study, we developed SurfGNN, a surface-...
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous malignancy with poor prognosis and variable response to therapy. E...
The tumor vasculature is a dynamic and heterogeneous component of the tumor microenvironment (TME) that influences tumor progression, immune infiltrat...
BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive vascular disease characterized by immune dysregulation and pulmonary vascular remod...
BACKGROUND: Clinical empathy is essential for postgraduate nursing students. How it changes during clinical internships remains unclear. AIM: To explo...
BACKGROUND: High-altitude hypoxia (HAH) can cause adverse reactions, such as tinnitus and barotrauma, but the role of mitotic catastrophe (MC) in HAH ...
Peer review is the result of a long historical evolution. From the Greek philosophy (the metaphor of Socratic maieutics) to the Cartesian method of sy...
Spiking Neural Networks (SNNs) deployed on wearable devices can exhibit runaway firing when processing noisy electrocardiogram (ECG) signals, increasi...
Many individuals hospitalized due to severe viral infections develop mental and physical sequelae, which could potentially be prevented by targeted in...
INTRODUCTION: The combination of phototherapy (PTT/PDT) and immunotherapy holds promise for cancer treatment but is hindered by poor spatiotemporal co...
BACKGROUND: Survivors of pediatric intensive care often experience prolonged morbidity, but recovery trajectories and features associated with impairm...