Anemia

Copper transporters promote the malignant progression of glioblastoma by regulating the immunosuppressive tumour microenvironment via the SLC31A1-WNT5A axis.

BACKGROUND: The prognosis for patients with glioblastoma (GBM) remains extremely poor, a challenge l...

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma.

BACKGROUND: Nasopharyngeal carcinoma (NPC) is partially driven by epithelial-mesenchymal transition ...

Computational Model for Predicting Optimal Clinical Intervention in Pre-Operative Neonates with Transposition of the Great Arteries.

PURPOSE: Transposition of the Great Arteries (TGA) is a congenital heart defect characterized by the...

Machine learning and SHAP interpretation to identify high-level compassion fatigue among operating room nurses: a multicenter cross-sectional study.

BACKGROUND: Operating room nurses (ORNs) are at high risk for compassion fatigue (CF), which signifi...

Sustainable Synaptic Device with Two-Dimensional Ferroelectric Materials for Neuromorphic Computing.

To overcome the coming big-data era, significant efforts are needed to implement neuromorphic comput...

Modulation of tumor-derived exosomes and reprogramming of cancer-associated fibroblasts for colorectal cancer therapy.

Hypoxia is pervasive within the solid tumor microenvironment (TME), reshaping it through exosome rel...

Beyond Diagnosis: A Systematic Review of Artificial Intelligence and Deep Learning in Monitoring Iron Overload and Organ Toxicity in Beta-Thalassemia.

Transfusion-dependent β-thalassemia (B-TM) is complicated by progressive iron overload, remaining a ...

Adaptive multimodal learning for driver cognitive state monitoring using transformer-based fusion with personalized meta-learning and federated optimization.

Road accidents caused by driver fatigue and cognitive overload remain a significant public safety co...

Topological data analysis improves estimation of muscle fatigue and contraction level from surface electromyography data.

ObjectiveMuscle fatigue affects individuals with neuromuscular disease and elite athletes alike. Mus...

Mutational signatures in blood-brain barrier: mechanisms, computational insights, and clinical applications in precision oncology.

The blood - brain barrier (BBB) plays a central role in maintaining central nervous system (CNS) hom...

Assessment models for driving comfort and fatigue status based on heart rate variability.

OBJECTIVES: This study, from an interdisciplinary perspective of human factors engineering and biome...

Evaluation of basic life support practice skills based on artificial intelligence technology: system construction and evaluation equivalence validation.

BACKGROUND: Basic life support (BLS) skills are the core competencies of healthcare professionals in...

The effects of fatigue on the relation between ocular pursuit and interceptive performance in soccer experts.

Accuracy and duration of ocular pursuit of a target object have been linked to interceptive performa...

Quantitative whole-body measurement of inflammothrombotic immunologic response disease using Fleming method for tissue and vascular differentiation and metabolism.

BACKGROUND: Precision theranostics in nuclear medicine requires reproducible, calibrated quantificat...

Identifying Biomarkers Using a Portable, Home-Based Eye-Tracking System to Predict Short-Term Visual Fatigue Deterioration: Prospective Observational Feasibility Study.

BACKGROUND: The escalating prevalence of screen-related eye fatigue has become a health burden in th...

Machine learning models for predicting childhood anemia in Mozambique: analysis from national survey data.

Parametrically upscaled model-based predictive platform for fatigue with location-specific microstructural linkages.

Fatigue in metallic materials is a cost-intensive engineering challenge due to unpredictable occurre...

A deep dive into ferritin nanoparticle advancements: experimental and computational perspectives.

Ferritin, a natural iron-storage protein, has emerged as a versatile platform in nanotechnology and ...

FOSL2 regulates endothelial cell state and chromatin accessibility in systemic sclerosis pulmonary vascular remodeling.

Systemic sclerosis (SSc) is characterized by fibrosis and vasculopathy affecting the skin and intern...

Physiological predictors of respiratory motor plasticity: A machine-learning reappraisal of phrenic motor facilitation.

Acute intermittent hypoxia (AIH)-induced phrenic long-term facilitation (pLTF) is a well-established...

Nanomaterials reshaping cancer radiotherapy: Radiosensitization mechanisms, delivery and theranostic platforms, multimodal synergy, and clinical translation strategies.

Radiotherapy (RT) remains a cornerstone of cancer management but is fundamentally constrained by nor...