Latest AI and machine learning research in atherosclerosis for healthcare professionals.
Huntington's disease (HD) is a rare, inherited neurodegenerative disorder caused by the expanded CAG repeats in the huntingtin gene. The HD domain still lacks detailed knowledge of validated drug targets, limiting the effectiveness of classical methods. To address this gap, we have applied an integrated computational approach, combining machine learning (ML) with transcriptomic analysis, to identi...
Amyloid fibrils formed by the misfolding and aggregation of proteins are a pathological hallmark of many neurodegenerative conditions including Alzheimer's disease (AD). Although recent studies have shown that pre-fibrillar species including low molecular-weight oligomers are more toxic in vitro than mature fibrils, and correlate better with cognitive decline in AD patients, techniques to study th...
BACKGROUND: Accurate individual risk assessment is crucial for guiding and improving the prevention of atherosclerotic cardiovascular disease (ASCVD)....
BACKGROUND: Current liver cancer screening in Korea focuses on viral hepatitis or cirrhosis, despite rising risks from metabolic and alcohol-related l...
Effective treatment of diabetic osteoporotic fractures (DOF) requires biomaterials capable of promoting vascularized bone regeneration. A biodegradabl...
INTRODUCTION: Frequent anti-vascular endothelial growth factor (anti-VEGF) injections for the treatment of neovascular age-related macular degeneratio...
This study aimed to investigate the value and difference in predictive performance between ophthalmologists and a previously developed and validated a...
BACKGROUND: Cardiovascular disease screening faces significant challenges in resource-limited settings, where infrastructure and computational constra...
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, appearing to be associated with accelerated brain aging. Althoug...
Perivascular adipose tissue (PVAT) is a metabolically active tissue that influences vascular function through paracrine signaling of adipokines. Patho...
BACKGROUND: Dementia and Parkinson's disease (PD) are among the most prevalent neurological disorders globally. Most previous research has focused on ...
Rapid industrial and agricultural intensification is increasing multi-source heavy metals (HMs) inputs into farmland, escalating risks to soil-crop sy...
Due to the unpredictability of loads and the complexity of fault propagation, modern power distribution networks require advanced technologies for fau...
BACKGROUND: An increasing number of patients with abdominal aortic aneurysms (AAAs) are opting for endovascular aneurysm repair (EVAR), and predicting...
Acute ischemic stroke (AIS) outcomes depend critically on rapid, accurate early diagnosis in the emergency department. Traditional prehospital tools a...
BACKGROUND: One of the main causes of blindness in the world, diabetic retinopathy (DR) is a dangerous condition that impairs vision in diabetics. Pre...
Vascular dementia (VaD) is the second most common type of dementia, yet its pathogenesis is not fully understood, and effective diagnostic and therape...
STUDY DESIGN: A retrospective multicenter study. OBJECTIVE: To identify independent risk factors for spinal epidural lipomatosis (SEL) and to develop ...
Coronary artery disease (CAD) remains a leading cause of mortality and morbidity worldwide. Coronary artery calcification (CAC) is a well-established ...