Cardiovascular

Atherosclerosis

Latest AI and machine learning research in atherosclerosis for healthcare professionals.

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ShenLingBaiZhu powder ameliorates obesity and atherosclerosis by inhibiting inflammation and apoptosis through the suppression of the TLR4/NF-κB pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: ShenLingBaiZhu Powder (SLBZP) is a renowned traditional Chinese medicinal formula that has been historically and clinically applied for managing obesity (OB) and atherosclerosis (AS). Nevertheless, its precise molecular mechanisms remain to be fully elucidated. AIM OF THE STUDY: To systematically clarify the material basis and multi-target mechanisms of SLBZP agains...

Jan 19 2026 41564986

Machine Learning Prediction of Chronic Kidney Disease in Elderly MetS Patients Using NHANES 2011-2020 Data.

BACKGROUND: Chronic kidney disease (CKD) is getting more common in elderly people with metabolic syndrome, but early detection and risk prediction are still hard. So we created and validated a CKD risk prediction model tailored for these patients to get past the limits of existing clinical screening tools. METHODS: We used data from the National Health and Nutrition Examination Survey and the Chin...

Jan 19 2026 41371294
Systemic Microvasculature Frailty: Brain frailty score predicts contrast-associated acute kidney injury after thrombectomy for stroke.

BACKGROUND: Contrast-associated acute kidney injury (CA-AKI) is a frequent complication after mechanical thrombectomy (MT). Cerebral small vessel dise...

Jan 19 2026 41576834
Multimodal imaging of acquired aortic diseases: clinical efficacy, comparative analysis, and future perspectives.

Aortic diseases, particularly acute aortic syndromes (AAS) and aortic aneurysms (AA), represent critical cardiovascular conditions with high mortality...

Jan 19 2026 41549183
Symptom status and non-calcified plaque burden across CAC strata: insights from AI-based CCTA quantification.

To investigate whether non-calcified coronary plaque (NCP) volume differs between symptomatic versus asymptomatic individuals across strata of coronar...

Jan 19 2026 41549194
Lesion stratification with intracoronary imaging.

Intracoronary (IC) imaging-guided percutaneous coronary intervention (PCI) improves clinical outcomes in patients with high clinical and anatomical ri...

Jan 19 2026 41549684
Fibroblast-like cells accumulate late in human coronary atherosclerosis contributing to necrotic core formation.

AIMS: Proliferation of arterial smooth muscle cells (SMCs) and their modulation to alternative mesenchymal phenotypes is central to atherosclerotic le...

Jan 19 2026 41553378
Decoding Non-Neuronal Mechanisms and Therapeutic Targets in Huntington's Disease Through Integrative Transcriptomics and Machine Learning.

Huntington's disease (HD) is a rare, inherited neurodegenerative disorder caused by the expanded CAG repeats in the huntingtin gene. The HD domain sti...

Jan 19 2026 41553597
Fluorescence from dual molecular rotors allows sensitive detection of widespread brain pathology in a mouse model of Alzheimer's disease.

Amyloid fibrils formed by the misfolding and aggregation of proteins are a pathological hallmark of many neurodegenerative conditions including Alzhei...

Jan 19 2026 41553693
Machine learning and SHAP values for predicting coronary artery disease risk in Xinjiang, China.

BACKGROUND: Accurate individual risk assessment is crucial for guiding and improving the prevention of atherosclerotic cardiovascular disease (ASCVD)....

Jan 17 2026 41545835
Liver cancer risk stratification using deep learning on nationwide longitudinal health screening data: a retrospective cohort study.

BACKGROUND: Current liver cancer screening in Korea focuses on viral hepatitis or cirrhosis, despite rising risks from metabolic and alcohol-related l...

Jan 17 2026 41547794
Activating the SDF-1/CXCR4 axis: Notoginsenoside R1-Functionalized zinc scaffolds accelerate fracture healing and angiogenesis in diabetic osteoporosis.

Effective treatment of diabetic osteoporotic fractures (DOF) requires biomaterials capable of promoting vascularized bone regeneration. A biodegradabl...

Jan 16 2026 41579467
Budget Impact of Faricimab in Neovascular Age-Related Macular Degeneration in the Netherlands: A Systematic Review and Meta-Analysis of Injection Count.

INTRODUCTION: Frequent anti-vascular endothelial growth factor (anti-VEGF) injections for the treatment of neovascular age-related macular degeneratio...

Jan 16 2026 41543675
Artificial intelligence based prediction of first recurrence in neovascular age related macular degeneration with validation by 19 experts.

This study aimed to investigate the value and difference in predictive performance between ophthalmologists and a previously developed and validated a...

Jan 16 2026 41545508
Foundation models enable wearable signal screening for cardiovascular disease among people living with HIV.

BACKGROUND: Cardiovascular disease screening faces significant challenges in resource-limited settings, where infrastructure and computational constra...

Jan 16 2026 41545675
Accelerated brain aging in amyotrophic lateral sclerosis and its prognostic associations: a cohort study.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, appearing to be associated with accelerated brain aging. Althoug...

Jan 15 2026 41535829
Imaging and Quantification of Perivascular Adipose Tissue.

Perivascular adipose tissue (PVAT) is a metabolically active tissue that influences vascular function through paracrine signaling of adipokines. Patho...

Jan 15 2026 41537262
Co-occurrence patterns and related risk factors of dementia and Parkinson's disease among older adults across 204 countries and territories: a spatial correspondence and systematic analysis.

BACKGROUND: Dementia and Parkinson's disease (PD) are among the most prevalent neurological disorders globally. Most previous research has focused on ...

Jan 15 2026 41540403
Unveiling the fate of heavy metals along the soil-rice-human pathway: Source-sink quantification, rhizospheric processes, and health implications.

Rapid industrial and agricultural intensification is increasing multi-source heavy metals (HMs) inputs into farmland, escalating risks to soil-crop sy...

Jan 15 2026 41558351
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