Atherosclerosis

Individual risk assessment for rupture of abdominal aortic aneurysm using artificial intelligence.

OBJECTIVE: This study aimed to develop a prediction tool to identify abdominal aortic aneurysms (AAAs) at increased risk of rupture incorporating demographic, clinical, imaging, and medication data using artificial intelligence (AI).

Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek's disease virus with REV-LTR insertion.

Marek's Disease (MD), caused by Marek's disease virus (MDV), is a highly contagious lymphoproliferative disease in poultry. Despite the fact that MD has been effectively controlled by vaccines, the virulence of field isolates of MDV has continued to evolve, becoming more virulent under the immune pressure of vaccines. Our previous research has confirmed that the recombinant rMDV strain with REV-LT...

A bibliometric analysis of abdominal aortic aneurysm (2014-2024).

BACKGROUND: Abdominal aortic aneurysm (AAA) is a localized bulge of the abdominal aorta, which mainly manifests as a pulsatile mass in the abdomen. On...

Machine learning-based radiomic features of perivascular adipose tissue in coronary computed tomography angiography predicting inflammation status around atherosclerotic plaque: a retrospective cohort study.

OBJECTIVES: This study expolored the relationship between perivascular adipose tissue (PVAT) radiomic features derived from coronary computed tomograp...

Artificial intelligence in emergency neuroradiology: Current applications and perspectives.

Emergency neuroradiology provides rapid diagnostic decision-making and guidance for management for a wide range of acute conditions involving the brai...

3D electron microscopy for analyzing nanoparticles in the tumor endothelium.

Delivering medical agents to diseased tissues has been challenging, leading researchers to study the in vivo transport process in the body for improvi...

Integration of bulk/scRNA-seq and multiple machine learning algorithms identifies PIM1 as a biomarker associated with cuproptosis and ferroptosis in abdominal aortic aneurysm.

BACKGROUND: Abdominal aortic aneurysm (AAA) is a serious life-threatening vascular disease, and its ferroptosis/cuproptosis markers have not yet been ...

Revolutionary drug repositioning: the preventive and therapeutic potential of metformin and other antidiabetic drugs in age-related macular degeneration.

Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly worldwide. Anti-vascular endothelial growth factor (anti-VEGF...

TELEPROM Psoriasis: Enhancing patient-centered care and health-related quality of life (HRQoL) in moderate-to-severe plaque psoriasis.

BACKGROUND AND PURPOSE: Psoriasis is a chronic, immune-mediated inflammatory skin disease that significantly impacts patients' quality of life. The in...

Prediction of Two Year Survival Following Elective Repair of Abdominal Aortic Aneurysms at A Single Centre Using A Random Forest Classification Algorithm.

OBJECTIVE: The decision to electively repair an abdominal aortic aneurysm (AAA) involves balancing the risk of rupture, peri-procedural death, and lif...

Genomic analysis, culturing optimization, and characterization of bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.

Advances in bacteriophage genome sequencing and regulatory approvals of some bacteriophages in various applications have renewed interest in these ant...

Heparin in sepsis: current clinical findings and possible mechanisms.

Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immunity and other systems. Coagulation activation is ...

Cell-free plasma telomere length correlated with the risk of cardiovascular events using machine learning classifiers.

This retrospective study explored the association between circulating cell-free plasma telomere length (cf-TL) and coronary artery disease (CAD) and h...

Endothelial progenitor cells as an angiogenic biomarker for the diagnosis and prognosis of lung cancer.

BACKGROUND: Angiogenesis is mediated by endothelial progenitor cells (EPCs) derived from bone-marrow. In this prospective study, we tried to investiga...

The Effects of Perfluorooctanesulfonic acid (PFOS) on Human Umbilical Vein Endothelial Cells (HUVECs) Proliferation and Gene Expression and its Implications on Fetal Development.

Polyfluoro-alkyl substances (PFAS) are widely distributed environmental contaminants linked to human toxicity and developmental delays, especially low...

Cohort profile: AI-driven national Platform for CCTA for clinicaL and industriaL applicatiOns (APOLLO).

PURPOSE: Coronary CT angiography (CCTA) is well established for the diagnostic evaluation and prognostication of coronary artery disease (CAD). The gr...

Carotid Vessel Wall Segmentation Through Domain Aligner, Topological Learning, and Segment Anything Model for Sparse Annotation in MR Images.

Medical image analysis poses significant challenges due to limited availability of clinical data, which is crucial for training accurate models. This ...

Integrating Metabolomics Domain Knowledge with Explainable Machine Learning in Atherosclerotic Cardiovascular Disease Classification.

Metabolomic data often present challenges due to high dimensionality, collinearity, and variability in metabolite concentrations. Machine learning (ML...

Oral Microbe Community and Pyramid Scene Parsing Network-based Periodontitis Risk Prediction.

BACKGROUND: Periodontitis (PD) is a common chronic inflammatory disease affecting the gums and supporting tooth structures. It is often diagnosed only...

Automated machine learning for image-based detection of dental plaque on permanent teeth.

INTRODUCTION: To detect dental plaque, manual assessment and plaque-disclosing dyes are commonly used. However, they are time-consuming and prone to h...