Atherosclerosis

Unsupervised machine learning analysis of optical coherence tomography radiomics features for predicting treatment outcomes in diabetic macular edema.

This study aimed to identify distinct clusters of diabetic macular edema (DME) patients with differential anti-vascular endothelial growth factor (VEGF) treatment outcomes using an unsupervised machine learning (ML) approach based on radiomic features extracted from pre-treatment optical coherence tomography (OCT) images. Retrospective data from 234 eyes with DME treated with three anti-VEGF thera...

Identification of key therapeutic targets in nicotine-induced intracranial aneurysm through integrated bioinformatics and machine learning approaches.

BACKGROUND: Intracranial aneurysm (IA) is a critical cerebrovascular condition, and nicotine exposure is a known risk factor. This study delves into the toxicological mechanisms of nicotine in IA, aiming to identify key biomarkers and therapeutic targets.

Machine Learning-Based Prediction of Unplanned Readmission Due to Major Adverse Cardiac Events Among Hospitalized Patients with Blood Cancers.

BackgroundHospitalized patients with blood cancer face an elevated risk for cardiovascular diseases caused by cardiotoxic cancer therapies, which can ...

Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma.

BACKGROUND: Increasing evidence indicates a connection between intracranial aneurysm (intracranial aneurysm, IA) and autoimmune diseases. However, the...

Predicting Intraoperative Burst Suppression Using Preoperative EEG and Patient Characteristics.

Burst suppression (BS) is an electroencephalogram (EEG) pattern observed in patients undergoing general anesthesia. The occurrence of BS is associated...

Predicting cerebral infarction and transient ischemic attack in healthy individuals and those with dysmetabolism: a machine learning approach combined with routine blood tests.

Ischemic cerebral infarction is the most prevalent type of stroke, causing significant disability and death worldwide. Transient ischemic attack (TIA)...

Investigating long-term risk of aortic aneurysm and dissection from fluoroquinolones and the key contributing factors using machine learning methods.

The connection between fluoroquinolones and severe heart conditions, such as aortic aneurysm (AA) and aortic dissection (AD), has been acknowledged, b...

Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0-3 and the development of a machine learning prediction model: a nationwide prospective cohort study.

BACKGROUND: The American Heart Association recently introduced the concept of cardiovascular-kidney-metabolic (CKM) syndrome, highlighting the increas...

Artificial Intelligence in CT Angiography for the Detection of Coronary Artery Stenosis and Calcified Plaque: A Systematic Review and Meta-analysis.

PURPOSE: We aimed to evaluate the diagnostic performance of artificial intelligence (AI) in detecting coronary artery stenosis and calcified plaque on...

Risk Factors and Outcomes of Hemorrhagic Transformation in Acute Ischemic Stroke Following Thrombolysis: Analysis of a Single-Center Experience and Review of the Literature.

: This is a retrospective study conducted at the Clinical County Hospital of Craiova, Romania, providing valuable insights into hemorrhagic transforma...

AI-enabled opportunistic measurement of liver steatosis in coronary artery calcium scans predicts cardiovascular events and all-cause mortality: an AI-CVD study within the Multi-Ethnic Study of Atherosclerosis (MESA).

INTRODUCTION: About one-third of adults in the USA have some grade of hepatic steatosis. Coronary artery calcium (CAC) scans contain more information ...

A potential supplemental indication of dipyridamole for contraception: Dipyridamole inhibits mouse sperm fertilization capacity in vitro.

The inhibition of sperm cAMP and ATP levels, using an FDA-approved medication, may impair sperm motility and, consequently, fertilization, thus paving...

Analysis and validation of hub genes for atherosclerosis and AIDS and immune infiltration characteristics based on bioinformatics and machine learning.

Atherosclerosis is the major cause of cardiovascular diseases worldwide, and AIDS linked with chronic inflammation and immune activation, increases at...

Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C...

Reinforcement learning for safe autonomous two-device navigation of cerebral vessels in mechanical thrombectomy.

PURPOSE: Autonomous systems in mechanical thrombectomy (MT) hold promise for reducing procedure times, minimizing radiation exposure, and enhancing pa...

A domain adaptation model for carotid ultrasound: Image harmonization, noise reduction, and impact on cardiovascular risk markers.

Deep learning has been used extensively for medical image analysis applications, assuming the training and test data adhere to the same probability di...

The Influence of an AI-Driven Personalized Nutrition Program on the Human Gut Microbiome and Its Health Implications.

Personalized nutrition programs enhanced with artificial intelligence (AI)-based tools hold promising potential for the development of healthy and su...

AI-Quantitative CT Coronary Plaque Features Associate With a Higher Relative Risk in Women: CONFIRM2 Registry.

BACKGROUND: Coronary plaque features are imaging biomarkers of cardiovascular risk, but less is known about sex-specific patterns in their prognostic ...

Comparing machine learning models for osteoporosis prediction in Tibetan middle aged and elderly women.

The aim of this study was to establish the optimal prediction model by comparing the prediction effect of 6 kinds of prediction models containing bioc...

Quantifying the Unknowns of Plaque Morphology: The Role of Topological Uncertainty in Coronary Artery Disease.

This article aimed to explore topological uncertainty in medical imaging, particularly in assessing coronary artery calcification using artificial int...