Latest AI and machine learning research in autism for healthcare professionals.
Genome-wide association studies (GWAS) have identified hundreds of common genetic variants associated with regional brain volumes, enabling the construction of polygenic scores (PGS) that summarize genetic predisposition for variation in specific neuroanatomical traits. To investigate how these genetic influences are exerted spatially throughout the brain, we computed PGS for ten brain volume phen...
Electroretinography (ERG) measures the functional response of distinct retinal cells to light, but was largely displaced by structural imaging in the 2000s. Standardization efforts by the International Society for Clinical Electrophysiology of Vision (ISCEV) began in the late 1980s, and collapsed the rich time-series traces into reproducible components and implicit times. Recent improvements in ha...
Autism spectrum disorder (ASD) is a developmental disability characterized by challenges in social interaction and communication. As the causes of ASD...
Objective: Erythropoietic protoporphyria (EPP) is a rare photodermatosis marked by multi-year diagnostic delays. We developed and externally validated...
Photosynthesis is among the most consequential yet genetically complex traits in crop plants, and translating its natural variation into actionable ge...
Isocitrate dehydrogenase (IDH) mutant gliomas often transform from low to high grade aggressive tumors. The genetic and molecular drivers of this Mali...
Objective: Foundation models represent the next advancement in AI for EEG analysis; however current explainable AI techniques provide attribution scor...
Dance imitation integrates motor planning, sensorimotor integration, and social cognition, offering a sensitive framework to characterize motor behavi...
Background: Accurate segmentation of the Left Anterior Descending (LAD) artery in 3D free-breathing, non-contrast CT is critical for cardiac dose spar...
AI-assisted facial phenotyping supports rare genetic disorder prioritization by retrieving visually similar diagnosed cases from facial image referenc...
Root anatomical barriers, including the suberized and lignified walls of the endodermis and exodermis, and cortical aerenchyma, regulate water and nut...
Neuroimaging and genetic testing are two important clinical references for nervous system diseases, offering complementary diagnostic information. How...
Background & Aims: Haematoxylin and eosin (H&E) staining remains the diagnostic gold standard for solid cancers, including hepatocellular carcinoma, a...
Background: Genome wide association studies (GWAS) often fail to identify higher-order epistatic interactions that contribute to complex inheritance p...
Single-cell RNA sequencing (scRNA-seq) simultaneously provides gene-expression profiles and genetic variants from individual cells, creating an opport...
Deep learning models applied to DNA sequences have achieved success in predicting gene expression, chromatin profiles, and variant pathogenicity. Howe...
Leaves maintain hydraulic homeostasis during photosynthesis through the coordinated action of stomata, which regulate gas exchange and transpiration, ...
Genome-wide studies of cardiac structure and function have relied on global imaging metrics that fail to capture the full complexity of myocardial beh...
In practical settings, medical image segmentation models are often developed with limited annotated data rather than fully labeled datasets. Training ...
Right ventricular (RV) trabeculation may reflect adaptation to loading conditions and imprinting of early developmental processes, yet its genetic det...