Autism

Abnormalities of brain dynamics based on large-scale cortical network modeling in autism spectrum disorder.

Synaptic increase is a common phenomenon in the brain of autism spectrum disorder (ASD). However, th...

The interaction of UBR4, LRP1, and OPHN1 in refractory epilepsy: Drosophila model to investigate the oligogenic effect on epilepsy.

Refractory epilepsy is an intractable neurological disorder that can be associated with oligogenic/p...

Expanding biobank pharmacogenomics through machine learning calls of structural variation.

Biobanks linking genetic data with clinical health records provide exciting opportunities for pharma...

Multi-Disease Deep Learning Framework for GWAS: Beyond Feature Selection Constraints

Traditional GWAS has advanced our understanding of complex diseases but often misses nonlinear gen...

Deep learning analyses of splicing variants identify the link of PCP4 with amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a severe motor neuron disease, with most sporadic cases lacki...

Advancing Amorphous Solid Dispersions Design: Insights into Dissolution Kinetics via Thermodynamic Descriptor and Machine Learning.

Amorphous solid dispersions (ASD) are an effective strategy for enhancing the solubility and bioavai...

AI-driven Web Application for Early Detection of Sudden Death Syndrome (SDS) in Soybean Leaves Using Hyperspectral Images and Genetic Algorithm

Sudden Death Syndrome (SDS), caused by Fusarium virguliforme, poses a significant threat to soybea...

Genetic Features for Drug Responses in Cancer -- Investigating an Ensemble-Feature-Selection Approach

Predicting drug responses using genetic and transcriptomic features is crucial for enhancing perso...

Genomic language models (gLMs) decode bacterial genomes for improved gene prediction and translation initiation site identification.

Accurate bacterial gene prediction is essential for understanding microbial functions and advancing ...

Does alignment alone predict mechanical complications after adult spinal deformity surgery? A machine learning comparison of alignment, bone quality, and soft tissue.

OBJECTIVE: Mechanical complications are a vexing occurrence after adult spinal deformity (ASD) surge...

Innovations in Quail Welfare: Integrating Environmental Enrichment, Nutrition and Genetic Advances for Improved Health and Productivity.

The demand for ethical and sustainable poultry production is driving up the importance of quail welf...

Advances in viral vector-based delivery systems for gene therapy: a comprehensive review.

Gene therapy offers a revolutionary approach for treating genetic and acquired disorders by deliveri...

Prenatal exposure to criteria air pollution and traffic-related air toxics and risk of autism spectrum disorder: A population-based cohort study of California births (1990-2018).

BACKGROUND: Autism spectrum disorder (ASD) prevalence has risen steadily in California (CA) over sev...

Precision medicine applications in dilated cardiomyopathy: Advancing personalized care.

Dilated cardiomyopathy (DCM) is a prevalent cardiac disorder affecting 1 in 250-500 individuals, cha...

Artificial intelligence in autism spectrum disorder: A path to early detection and improved outcomes.

A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types.

Considering the high incidence of osteoarthritis (OA), especially of the knee and hip, this study ex...

Self-training EEG discrimination model with weakly supervised sample construction: An age-based perspective on ASD evaluation.

Deep learning for Electroencephalography (EEG) has become dominant in the tasks of discrimination an...

From classical approaches to artificial intelligence, old and new tools for PDAC risk stratification and prediction.

Pancreatic ductal adenocarcinoma (PDAC) is recognized as one of the most lethal malignancies, charac...

Community-Based Efficient Algorithms for User-Driven Competitive Influence Maximization in Social Networks

Nowadays, people in the modern world communicate with their friends, relatives, and colleagues thr...

Fetal Sleep: A Cross-Species Review of Physiology, Measurement, and Classification

Fetal sleep is a relatively underexplored yet vital aspect of prenatal neurodevelopment. Understan...

[Methodological breakthroughs and challenges in research of soil phage microecology].

Phages, as obligate bacterial and archaeal parasites, constitute a virus group of paramount ecologic...