Neurology

Autism

Latest AI and machine learning research in autism for healthcare professionals.

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DANCE: An open-source analysis pipeline and low-cost hardware to quantify aggression and courtship in Drosophila

Quantifying animal behavior is pivotal for identifying the underlying neuronal and genetic mechanism...

Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders

Aberrant biomolecular condensates are implicated in multiple incurable neurological disorders, inclu...

Predictive models of the genetic bases underlying budding yeast fitness in multiple environments

The ability of organisms to adapt and survive depends on the effects of genes and the environment on...

Multi-omics Integration of Microbiota Transplant Therapy in Children with Autism Spectrum Disorders

Microbiota transplant therapy (MTT) is a promising avenue for the substantial improvement of gastroi...

Cross-Species Morphology Learning Enables Nucleic Acid-Independent Detection of Live Mutant Blood Cells

In hematology/oncology clinics, molecular diagnostics based on nucleic acid sequencing or hybridizat...

Integrative machine learning predicts activating kinase mutations for precision oncology

Kinases are enzymes that catalyze phosphorylation and play crucial roles in a myriad of cellular reg...

Decoding the Energetic Logic of Genetic Systems: A Hybrid Neural-Symbolic Framework for Quantum-Informed Bioenergetics

Life is sustained by the dynamic flow of energy through adenosine triphosphate (ATP), redox carriers...

MRI-based classifier to identify close-to-onset cases in C9orf72 genetic frontotemporal dementia

Predicting symptom onset in genetic frontotemporal dementia (FTD) is crucial for advancing targeted ...

Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species

Proper brain function requires the assembly and function of diverse populations of neurons and glia....

Deep Learning-Based Genetic Perturbation Models Do Outperform Uninformative Baselines on Well-Calibrated Metrics

Single cell genetic perturbation modeling involves predicting the effects of unobserved genetic mani...

Natural variation in IBF1 disrupts its interaction with CHS1 and affects metabolism of hulls in rice

Secondary metabolites in plants have various physiological functions, including antioxidant and anti...

Benchmarking DNA Foundation Models for Genomic and Genetic Tasks

The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive e...

Neuronal activity triggers widespread changes in RNA stability

Neuronal activity shapes brain development and refines synaptic connectivity in part through dynamic...

The Impact of Stability Considerations on Genetic Fine-mapping

Fine-mapping methods, which aim to identify genetic variants responsible for complex traits followin...

Iron Deficiency Impairs Mitochondrial Energetics and Early Axonal Growth and Branching in Developing Hippocampal Neurons

Each stage of neuronal development (i.e., proliferation, differentiation, migration, neurite outgrow...

scRGP: Prediction of Single-cell Genetic Perturbation Transcriptional Responses based on Rank in Multiple Scenarios

Single-cell perturbation sequencing technologies (e.g., Perturb-seq, CROP-seq), which integrate CRIS...

A validated set of neural gene reporter mice and chemical tracers tools for mapping knee innervating neurons

Joint pain is an increasing concern for our aging population, as current therapies to slow joint dis...

Genotype-phenotype modeling of light ecotypes in Prochlorococcus reveals genomic signatures of ecotypic divergence

Prochlorococcus is a cyanobacterial genus that exhibits photosynthetic capacity and remarkable genet...

Systematic discovery of single-cell protein networks in cancer with Shusi

Context-specific protein-protein interaction (PPI) drive heterogeneity of primary tumor, forming a f...

ADHD Medications and Preadolescent Brain Structure: Patterns of Cortical Attenuation from the ABCD Study

Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in th...

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