Infectious Disease

Bacterial Infection

Latest AI and machine learning research in bacterial infection for healthcare professionals.

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Showing 261-280 of 4,864 articles

Deep learning-based high-information-content graph representation of early stage bacterial biofilms.

Bacterial biofilms are complex, spatially organized microbial communities that exhibit enhanced resistance to antibiotics and contribute to chronic infections. Understanding their structure, especially during early formation stages, is critical for developing effective intervention strategies. Here, we present a high-resolution computational framework that models biofilms as undirected interaction...

Apr 3 2026 41932927

Medium-aware multi-task learning for robust bacterial identification using Raman spectroscopy.

Raman spectroscopy has demonstrated significant potential for rapid bacterial identification; however, bacterial spectral signatures are frequently confounded by complex culture medium background signals, leading to limited generalization under varying cultivation conditions. Conventional single-task deep learning models struggle to effectively decouple environmental noise, while training paradigm...

Apr 2 2026 41936345
Protein and genomic language models uncover the unexplored diversity of bacterial immunity.

The bacterial pangenome contains a vast diversity of antiphage systems, whose overall extent is still unknown. In this study, we developed complementa...

Apr 2 2026 41926572
DefensePredictor: A machine learning model to discover prokaryotic immune systems.

Antiphage defense systems protect bacteria from viral infection and have inspired important biotechnologies such as CRISPR-Cas9 while also revealing t...

Apr 2 2026 41926577
Bulk Microarray and Single-Cell Transcriptomic Analyses Reveal Bacterial Lipopolysaccharide-Related Biomarkers in Sepsis.

Sepsis, a life-threatening condition triggered by dysregulated host response to infection, poses significant global health challenges. Identifying lip...

Apr 1 2026 41649833
Transformer-based super-resolution lung CT images improve visualization of multiple diseases.

OBJECTIVES: To assess the Transformer-based Swin2SR model for super-resolution (SR) enhancement of lung CT images and its clinical potential. METHODS:...

Mar 30 2026 41915020
Digital holographic microscopy: use of artificial intelligence to enable rapid blood culture Gram stain digitization and interpretation.

Gram staining is one of the most commonly performed tests in the clinical microbiology laboratory. Results are used to both guide empiric antimicrobia...

Mar 30 2026 41910323
Structural and dynamic characterization of MirA-like xenosiderophore transporters in Fusarium: in silico modeling and in vitro validation.

Fusarium, an omnipresent fungus is known for its pathogenic potential. Pathogenic fungi like all other organisms need iron and are known to produce si...

Mar 30 2026 41910529
Adaptive acoustic streaming microbial system for oxytetracycline removal.

Microalgae-bacteria symbiosis has been demonstrated to possess the ability to remove antibiotics from water. Appropriate granulation strategies enhanc...

Mar 27 2026 41905672
Deciphering pharmaceutical resistance in sulfur-driven autotrophic denitrification: an integrated multi-omics artificial intelligence-driven structural biology approach.

Sulfur-driven autotrophic denitrification (SdAD) is a promising low-carbon technology for nitrogen removal; however, its stability and adaptive mechan...

Mar 26 2026 41921320
Integrating Molecular Dynamics and Deep Learning to Elucidate Conformational Plasticity Underlying the Reduced Activity of Glycocin F.

The escalating crisis of multidrug-resistant bacteria demands a new generation of antibiotics. Glycocin F (GccF), a potent bacteriocin, is a promising...

Mar 26 2026 41885711
Metagenomic profiling and predictive modeling of the gut microbiome reveal signatures of gestational disease.

The gut microbiome plays a vital role in maternal health and pregnancy outcomes, yet its impact on conditions like gestational hypertension (GH) and g...

Mar 25 2026 41879323
Harnessing the gut microbiota in extra-intestinal cancers: from causal evidence to immunotherapy strategies.

The gut microbiota (GM) has emerged as a key modulator of cancer development and therapeutic response beyond the gastrointestinal tract. In extra-inte...

Mar 24 2026 41873461
Nanogels for the targeted delivery of antibiotic and antimicrobial drugs.

Nanoparticle-based drug delivery systems represent a promising platform for advancing biomedical therapies. Among them, nanogels - three‑dimensional, ...

Mar 24 2026 41873797
Quaternized polysaccharides: A focused review on molecular engineering, antimicrobial mechanisms, and advanced applications.

The escalating threat of antibiotic resistance has intensified the search for sustainable antimicrobial alternatives. Quaternized polysaccharides, a c...

Mar 23 2026 42002324
Mapping the subgingival HerBiome and HisBiome over the human healthspan.

BACKGROUND: Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of...

Mar 23 2026 41867064
Early detection of ampicillin susceptibility in Enterococcus faecium with MALDI-TOF MS and machine learning.

BACKGROUND: Enterococcus faecium can cause severe infections and is often resistant to the first-line antibiotic ampicillin. Consequently, clinicians ...

Mar 20 2026 41866023
Biophysical properties and phenotypes of cell clusters detached from Staphylococcus epidermidis biofilms after matrix-targeted disruption.

Bacterial cells detached from Staphylococcus epidermidis biofilms are found to release predominantly as small oblate clusters (∼1.9 µm) in both untrea...

Mar 19 2026 41865609
Predicting oil contamination in water using machine learning on microbial compositions.

We present a compact and generative machine-learning framework that predicts oil contamination based on microbial community compositions from experime...

Mar 19 2026 41855210
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