Bacterial Infection

Automating wound assessment: convolutional neural network-based mobile application for SINBAD classification system.

INTRODUCTION: Diabetic foot ulcer (DFU) assessment using the SINBAD system is essential for clinical decision-making but often limited by access to specialists. This study presents a mobile application powered by a lightweight Convolutional Neural Networks (MobileNetV3 Small) to automate DFU classification. METHODS: A dataset of 996 clinician-labeled DFU images was used to train the model to class...

Machine Learning in Microbiome Research and Engineering.

Microbiomes, complex communities of microorganisms and their genetic material, hold immense potential for addressing global challenges in diverse sectors, including healthcare, agriculture, and bioproduction. Engineering these intricate ecosystems, however, necessitates a comprehensive understanding of the complex web of microbial interactions. The emergence of machine learning (ML) has revolution...

Boosting Array-based Diagnosis of Urinary Tract Infections via a Heterobifunctional Bridge-Driven Strategy.

Array-based sensing platforms have witnessed significant progress in recent years, demonstrating considerable potential for high-throughput and multip...

Supragingival Biomarker flora of Children With and Without Cariogenic Disease and Black Stains, Aged 3 to 6 Years.

BACKGROUND: The oral microbiome plays a pivotal role in the occurrence and progression of dental caries and black stain (BS) pigment. OBJECTIVES: The ...

AI-Based Exhaled VOC Panels as Gut Microbiota-Derived Biomarkers for IBD Screening.

Inflammatory bowel diseases (IBD) present significant diagnostic and therapeutic challenges due to their heterogeneity. Here, we analyze exhaled volat...

SemiRaman: A self-supervised contrastive representation learning-based framework for semi-supervised Raman spectral identification of pathogenic bacteria.

Raman spectroscopy has established itself as a robust and non-invasive approach for the precise identification of pathogenic bacteria. The fusion of R...

Unveiling Putative Functions of Burkholderia pseudomallei K96243 Hypothetical Proteins Via High-Throughput Characterization of Structural Similarities.

Burkholderia pseudomallei (BP) infections claims tens of thousands of lives worldwide every year. The bacterium's distinctive characteristics include ...

Population heterogeneity revealed in morphometric analysis of densely populated microbial swarm collectives.

UNLABELLED: Uncovering cell morphology within communities is crucial to understanding how collective groups of organisms can function and adapt to the...

Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis.

Sepsis, a life-threatening syndrome caused by dysregulated host responses to infection, lacks effective therapeutic strategies due to its complex immu...

New insights into machine learning prediction techniques for real-time sanitary risk assessment in karst drinking water sources affected by faecal contamination.

Safe drinking water supply from karst aquifers faces several challenges due to their high vulnerability to contamination, which can result in abrupt w...

Combatting antimicrobial-resistant Neisseria gonorrhoeae: new antibiotics and the pipeline of antigonococcal therapeutics.

PURPOSE OF REVIEW: Gonorrhea is the second most prevalent bacterial sexually transmitted infection globally. The proliferation of antimicrobial-resist...

Characteristics and genomics study of Salmonella isolates in retail chicken in Shaanxi, China: Focus on comparative genomics analysis of S. Kentucky and S. enteritidis isolates from Shaanxi with those from elsewhere in China.

Salmonella is a major foodborne pathogen, frequently linked to poultry and posing serious food safety and public health risks. To investigate its epid...

Machine learning-augmented metaproteomics reveals metabolic adaptation of anammox bacteria under high nitrogen loading rate.

Anaerobic ammonium oxidation (anammox) is a biological process in which NH4+ serves as the electron donor and NO2- as the electron acceptor to produce...

Regulatory mechanism of the oprM gene in colistin resistance of acinetobacter baumannii.

BACKGROUND: Colistin resistance in Acinetobacter baumannii (AB) is a serious clinical concern. This study aimed to identify resistance-related genes a...

Near real-time and next-day prediction for Escherichia coli (E. coli) concentrations in highly urbanized watersheds.

Microbial contamination of heavily urbanized watersheds is of significant public health concern. Escherichia coli (E. coli) is frequently traced as a ...

Modeling typhoid dynamics using recurrent neural networks with Bayesian regularization.

The current research provides the numerical investigation of the epidemic typhoid model by using the stochastic artificial intelligence-based recurren...

Nationwide longitudinal evaluation of a machine learning approach for enhanced interpretation of Xpert MTB/RIF ultra rifampicin-resistance results in low bacterial load tuberculosis specimens.

BACKGROUND: The World Health Organization (WHO) has identified tuberculosis (TB) as the leading cause of death from a single infectious agent. False-p...

Influence of typical anions in brackish water on synergistic remediation of Vanadium(V) by coffee grounds and Ryegrass: Machine learning modeling and co-occurrence network analysis.

Brackish water is widely distributed and highly overlaps with areas contaminated by vanadium (V), presenting multiple challenges for V pollution remed...

Effective alternative strategies to combat challenges associated with MDR bacterial infections: Drug repurposing, role of artificial intelligence, and novel therapeutic options.

Antibiotic failure has emerged as a critical global health concern, driven by a combination of factors including the stagnation in the discovery of ne...

Ligand-based prediction of anti-bacterial compounds: Overcoming class imbalance in molecular data.

In the emergence of pan-drug-resistant bacteria, there is an urgent demand for the discovery of structurally novel antibiotics. While traditional drug...