Bacterial Infection

The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and modeling to identify new therapeutics.

Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis can develop from bacterial (gram negative or gram positive), fungal or viral (such as COVID) infections. However, therapeutics developed in animal models and traditional sepsis models have had li...

Anti-ultraviolet, antibacterial, and biofilm eradication activities against of melanins and melanin derivatives from and .

and produced significant amounts of water-insoluble melanins, and our previous study successfully enhanced their water solubility by arginine modification. This research aimed to investigate the anti-ultraviolet, antibacterial, and biofilm eradication activities of both the melanins and arginine-modified melanin (melanin derivatives) from these two fungi against an acne-causing bacterium (). Apa...

The antibacterial activity of berberine against : its therapeutic potential in inflammatory acne.

() is a major pathogen implicated in the evolution of acne inflammation. Inhibition of -induced inflammation is a prospective acne therapy strategy. ...

BactInt: A domain driven transfer learning approach for extracting inter-bacterial associations from biomedical text.

BACKGROUND: The healthy as well as dysbiotic state of an ecosystem like human body is known to be influenced not only by the presence of the bacterial...

ML-FGAT: Identification of multi-label protein subcellular localization by interpretable graph attention networks and feature-generative adversarial networks.

The prediction of multi-label protein subcellular localization (SCL) is a pivotal area in bioinformatics research. Recent advancements in protein stru...

GATR-3, a Peptide That Eradicates Preformed Biofilms of Multidrug-Resistant .

is a gram-negative bacterium that causes hospital-acquired and opportunistic infections, resulting in pneumonia, sepsis, and severe wound infections ...

Characterization of extended-spectrum beta-lactamase and carbapenemase genes in bacteria from environment in Burkina Faso.

INTRODUCTION: This study aimed to characterize extended-spectrum beta-lactamase (ESBL) and carbapenemase genes in bacteria from the environment in Bob...

Pregnancy-associated asymptomatic bacteriuria and antibiotic resistance in the Maternity and Children's Hospital, Arar, Saudi Arabia.

INTRODUCTION: The Ministry of Health in Saudi Arabia provides comprehensive antenatal care for all pregnant women with all required investigations. Ho...

Effects of Mannosylerythritol-Lipids-B on ATCC 6919.

Mannosylerythritol-lipids-B (MEL-B) are microbial-produced glycolipids with skincare properties, notably moisturizing, antimelanogenic, antimicrobial,...

Procalcitonin Levels in Identifying Bacterial Infections in Children with and without COVID-19.

OBJECTIVE: Elevated procalcitonin levels have been associated with bacterial infection in children. Observational studies reported high procalcitonin ...

Development of optimized functional clove fortified probiotic yoghurt.

We focused on assessing the antimicrobial effects of functional yoghurts supplemented with clove and probiotics. The formulation of aqueous clove extr...

Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.

Studies suggest that mangiferin (MAF) has good therapeutic effects on chronic bronchitis and hepatitis. Also, it is one of the antiviral ingredients i...

Antibiotic resistance gene-free probiont administration to tilapia for growth performance and resistance.

BACKGROUND AND AIM: The rapid development of aquaculture as a major food sector is accompanied by challenges, including diseases that affect tilapia f...

Use of Organic Acids to Control and Infection in Swine Jowl Fat.

The objective of this work was to evaluate the mortality of and inoculated in fresh swine jowls treated with different concentrations of organic aci...

Improved antimicrobial activities of essential oils nanoencapsulated into hydroxypropyl-beta-cyclodextrins.

Natural antimicrobials have recently gained increasing interest over synthetic antimicrobials to overcome foodborne pathogens and food microbial conta...

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics.

From the traditional Chinese medicine point of view, although extract (HCE) possesses an incredible amount of phytonutrients and exhibits antioxidant...

Leveraging machine learning to distinguish between bacterial and viral induced pharyngitis using hematological markers: a retrospective cohort study.

Accurate differentiation between bacterial and viral-induced pharyngitis is recognized as essential for personalized treatment and judicious antibioti...

Investigating Novel IspE Inhibitors of the MEP Pathway in Mycobacterium.

In a recent effort to mitigate harm from human pathogens, many biosynthetic pathways have been extensively evaluated for their ability to inhibit path...

Advances in machine learning-based bacteria analysis for forensic identification: identity, ethnicity, and site of occurrence.

When faced with an unidentified body, identifying the victim can be challenging, particularly if physical characteristics are obscured or masked. In r...

Determination of ertapenem in plasma and ascitic fluid by UHPLC-MS/MS in cirrhotic patients with spontaneous bacterial peritonitis.

OBJECTIVES: Spontaneous bacterial peritonitis is a frequent severe complication in cirrhotic patients with ascites. Carbapenem antibiotics are current...