Infectious Disease

Bacterial Infection

Latest AI and machine learning research in bacterial infection for healthcare professionals.

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FoundedPBI: Using Genomic Foundation Models to predict Phage-Bacterium Interactions

The scalability of phage therapy as a viable alternative or complement to antibiotics is limited by ...

A genetically encoded local learning rule enables physical learning in engineered bacteria

Training physical neural networks directly in matter remains difficult because most platforms do not...

kinGEMs: A Robust and Scalable Framework forResource-Constraint Models through StochasticTuning of Deep Learning-Predicted KineticParameters

The construction of accurate enzyme-constrained genome-scale models (ecGEMs) remains a critical chal...

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Non-perturbative Bacterial Identification Directly from Solid Agar Plates Using Raman

Raman spectroscopy is a promising tool for microbial identification, yet its implementation in micro...

Rapid Bacterial Identification and Antibiotic Susceptibility Testing through Interferometry-based Surface Topography Measurement

Antimicrobial resistance poses a critical global health threat. For many bacterial infections, such ...

GCN-Mamba: Graph Convolutional Network with Mamba for Antibacterial Synergy Prediction

The escalating crisis of antimicrobial resistance necessitates novel therapeutic strategies, among w...

Bacterial proteome foundation model enhances functional prediction from enzymes to ecological interactions

Bacteria play fundamental roles in ecosystems, human health, and biotechnology. Although bacterial g...

dAMN: a genome scale neural-mechanistic hybrid model to predict bacterial growth dynamics

This study presents dAMN, a hybrid neural-mechanistic model that integrates neural networks with gen...

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Explainable AI for end-to-end pathogen target discovery and molecular design

Drug discovery is often constrained by target identification, a bottleneck especially acute in antim...

Eubiota: Modular Agentic AI for Autonomous Discovery in the Gut Microbiome

The gut microbiome regulates many aspects of human biology, including immunity and inflammatory dise...

Cross hybridization Inference for Phylogenetic Resolution (CIPHR)-FISH enables microbiome imaging with strain level taxonomic resolution

The spatial organization of microbial communities is a critical determinant of host-microbe interact...

Predicting Multi-Drug Resistance in Bacterial Isolates Through Performance Comparison and LIME-based Interpretation of Classification Models

The rise of Antimicrobial Resistance, particularly Multi-Drug Resistance (MDR), presents a critical ...

Deep learning extracts MoA-specific signatures from high-throughput images of chemically and genetically perturbed Corynebacteria

Tuberculosis (TB) is the worldwide leading infectious killer due to a single pathogen and increasing...

Metagenomic strain tracking reveals patterns of bacterial spread and the impact of water chlorination

Bacterial infections are a major cause of morbidity and mortality among children under five in low- ...

Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species

Pseudouridine ({Psi}) modifications are the most abundant RNA modifications; however, their distribu...

An enzyme-level benchmark based on environmental bacterial laccases for predicting contaminant fate in water

Bacterial laccases are widespread multicopper oxidases whose roles in the fate of anthropogenic chem...

Single-Cell Raman Profiling Enables Rapid Precision Phage Therapy Against Multidrug-Resistant Hypervirulent Klebsiella pneumoniae

Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) poses a severe global health thre...

Quantifying the oxygen preferences of bacterial communities using a metagenome-based approach

Oxygen is a primary driver of the distribution and activity of microbial life. Since oxygen levels a...

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