Infectious Disease

Bacterial Infection

Latest AI and machine learning research in bacterial infection for healthcare professionals.

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Showing 1639-1659 of 4,965 articles
Early detection of ampicillin susceptibility in Enterococcus faecium with MALDI-TOF MS and machine learning

Enterococcus faecium can cause severe infections and is often resistant to the first-line antibiotic...

AI-guided competitive docking for virtual screening and compound efficacy prediction

Machine learning has transformed how we predict protein structures and interactions, but its full po...

Multiplex mapping of protein-protein interaction interfaces

We describe peptide mapping through Split Antibiotic Resistance Complementation (SpARC-map), a metho...

Coenzyme A depletion causes antibiotic tolerance in Pseudomonas aeruginosa

The widespread use of antibiotics promotes both resistance and tolerance. While resistance enables b...

From sequence to signature: Machine learning uncovers multiscale feature landscapes that predict AMR across ESKAPE pathogens

Since the clinical introduction of antibiotics in the 1940s, antimicrobial resistance (AMR) has beco...

The Regional Landscape of the Human Colon Culturome in Health and Cystic Fibrosis

Cystic fibrosis (CF) alters gut physiology, yet its impact on microbial communities across colonic r...

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High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV

Accurate detection of mutations within bacterial species is critical for fundamental studies of micr...

Leveraging Deep Learning and MD Simulations to Decipher the Molecular Basis of Attenuated Activity in Glycocin F

The escalating crisis of multi-drug resistant bacteria demand a new generation of antibiotics. Glyco...

A lettuce receptor-like kinase recognizes the highly conserved heptapeptide motif within microbial NEP1-like proteins

Plants rely on cell surface immune receptors to detect microbial patterns and initiate effective def...

Phylogeny-agnostic strain-level prediction of phage-host interactions from genomes

Bacteriophages offer promising alternatives to antibiotics for treating drug-resistant infections an...

PanSpace: Fast and Scalable Indexing for Massive Bacterial Databases

Species identification is a critical task in agriculture, food processing, and health-care. The rapi...

Design of multimodal antibiotics using deep learning

The rise of antimicrobial resistance has rendered many treatments ineffective, posing serious public...

SARS-CoV-2 Variant-Dependent Alterations in Nasopharyngeal Microbiota and Host Inflammatory Response

The SARS-CoV-2 pandemic saw multiple outbreaks occur over short periods. This was linked to the viru...

Adapting CRISPR-associated transposons for rapid and high-throughput reverse genetics

CRISPR-associated transposons (CAST) use guide RNAs to direct their transposition and are being harn...

Reinforcement learning for adaptive control of phenotypically heterogeneous bacterial populations

Bacterial populations display extraordinary resilience to antibiotic stress, driven by diverse physi...

Cross-Molecular Active Learning for the Discovery of Antimicrobial Polyacrylamides

Antimicrobial resistance poses an urgent and increasing threat to global health. The development of ...

Confidence-based Prediction of Antibiotic Resistance at the Patient Level

Rapid and accurate diagnostics of bacterial infections are necessary for efficient treatment of anti...

Extending digital biology: bacterial survival and morphological heterogeneity under antibiotic stress

The morphology of bacteria is modified by antibiotic stress while also serving to survive the antibi...

Harnessing Interpretable Deep Learning to Predict Meropenem Resistance in Klebsiella pneumoniae

Antimicrobial resistance represents an escalating global healthcare threat, complicating treatment a...

Skin lipid chemistry influences host-microbiome-pathogen interactions in snake fungal disease (ophidiomycosis)

Within host-microbiome-pathogen systems, the host chemical microenvironment is often overlooked desp...

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