Brain Cancer

Glioblastoma and Solitary Brain Metastasis: Differentiation by Integrating Demographic-MRI and Deep-Learning Radiomics Signatures.

BACKGROUND: Studies have shown that deep-learning radiomics (DLR) could help differentiate glioblastoma (GBM) from solitary brain metastasis (SBM), but whether integrating demographic-MRI and DLR features can more accurately distinguish GBM from SBM remains uncertain.

Deep learning catheter tip locations for photoacoustic-guided cardiac interventions.

SIGNIFICANCE: Interventional cardiac procedures often require ionizing radiation to guide cardiac catheters to the heart. To reduce the associated risks of ionizing radiation, photoacoustic imaging can potentially be combined with robotic visual servoing, with initial demonstrations requiring segmentation of catheter tips. However, typical segmentation algorithms applied to conventional image form...

Unsupervised machine learning models reveal predictive clinical markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation.

BACKGROUND: Glioblastoma is a malignant brain tumor requiring careful clinical monitoring even after primary management. Personalized medicine has sug...

Framework for Radiation Oncology Department-wide Evaluation and Implementation of Commercial Artificial Intelligence Autocontouring.

PURPOSE: Artificial intelligence (AI)-based autocontouring in radiation oncology has potential benefits such as standardization and time savings. Howe...

Exploring Capabilities of Large Language Models such as ChatGPT in Radiation Oncology.

PURPOSE: Technological progress of machine learning and natural language processing has led to the development of large language models (LLMs), capabl...

Enhancing Safety in AI-Driven Cone Beam CT-based Online Adaptive Radiation Therapy: Development and Implementation of an Interdisciplinary Workflow.

PURPOSE: The emerging online adaptive radiation therapy (OART) treatment strategy based on cone beam computed tomography allows for real-time replanni...

Multi-class glioma segmentation on real-world data with missing MRI sequences: comparison of three deep learning algorithms.

This study tests the generalisability of three Brain Tumor Segmentation (BraTS) challenge models using a multi-center dataset of varying image quality...

Current Strengths and Weaknesses of ChatGPT as a Resource for Radiation Oncology Patients and Providers.

PURPOSE: Chat Generative Pre-Trained Transformer (ChatGPT), an artificial intelligence program that uses natural language processing to generate conve...

Screening the phytotoxicity of micro/nanoplastics through non-targeted metallomics with synchrotron radiation X-ray fluorescence and deep learning: Taking micro/nano polyethylene terephthalate as an example.

Microplastics (MPs) and nanoplastics (NPs) are global pollutants with emerging concerns. Methods to predict and screen their toxicity are crucial. Ele...

Healthcare Professional Association Agency in Preparing for Artificial Intelligence: A Multiple-Case Study of Radiation Medicine and Medical Imaging in the Canadian context.

As artificial intelligence (AI) is increasingly integrated in healthcare, it is incumbent on healthcare professional associations (HPAs) to assist the...

A transformer-based multi-task deep learning model for simultaneous infiltrated brain area identification and segmentation of gliomas.

BACKGROUND: The anatomical infiltrated brain area and the boundaries of gliomas have a significant impact on clinical decision making and available tr...

Predicting meningioma grades and pathologic marker expression via deep learning.

OBJECTIVES: To establish a deep learning (DL) model for predicting tumor grades and expression of pathologic markers of meningioma.

Emerging trends in post-translational modification: Shedding light on Glioblastoma multiforme.

Recent multi-omics studies, including proteomics, transcriptomics, genomics, and metabolomics have revealed the critical role of post-translational mo...

Interpreting deep learning models for glioma survival classification using visualization and textual explanations.

BACKGROUND: Saliency-based algorithms are able to explain the relationship between input image pixels and deep-learning model predictions. However, it...

Artificial Intelligence-Based Organ Delineation for Radiation Treatment Planning of Prostate Cancer on Computed Tomography.

PURPOSE: Meticulous manual delineations of the prostate and the surrounding organs at risk are necessary for prostate cancer radiation therapy to avoi...

Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images.

Current diagnosis of glioma types requires combining both histological features and molecular characteristics, which is an expensive and time-consumin...

MGMT promoter methylation status prediction using MRI scans? An extensive experimental evaluation of deep learning models.

The number of studies on deep learning for medical diagnosis is expanding, and these systems are often claimed to outperform clinicians. However, only...

Automation and artificial intelligence in radiation therapy treatment planning.

Automation and artificial intelligence (AI) is already possible for many radiation therapy planning and treatment processes with the aim of improving ...

TumorDetNet: A unified deep learning model for brain tumor detection and classification.

Accurate diagnosis of the brain tumor type at an earlier stage is crucial for the treatment process and helps to save the lives of a large number of p...

Imaging biomarkers and radiomics in pediatric oncology: a view from the PRIMAGE (PRedictive In silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, Empowered by imaging biomarkers) project.

This review paper presents the practical development of imaging biomarkers in the scope of the PRIMAGE (PRedictive In silico Multiscale Analytics to s...