Oncology/Hematology

Breast Cancer

Latest AI and machine learning research in breast cancer for healthcare professionals.

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Automated Gross Tumor Volume (GTV) Contouring in High-Grade Gliomas Using a Deep Learning Approach.

RATIONALE AND OBJECTIVES: Accurate contouring of the Gross Tumor Volume (GTV) in High-Grade Gliomas (HGGs) is a cornerstone of effective Radiation Therapy (RT) planning, as it influences tumor control and spares normal tissue, thereby directly impacting treatment precision. However, the standard manual approach to GTV contouring requires considerable time and is prone to inter-observer variability...

Jan 15 2026 41545259

Image Quality Assessment of Artificial Intelligence Iterative Reconstruction for Low-dose Bronchial Artery CTA in Preoperative Hemoptysis Patients.

OBJECTIVES: To investigate the feasibility and image quality of artificial intelligence iterative reconstruction (AIIR) for computed tomography angiography (CTA) of the bronchial artery (BA) with a reduced radiation dose and contrast agent dosage. MATERIALS AND METHODS: A total of 110 hemoptysis patients were prospectively enrolled for bronchial artery CTA (BA-CTA) and were randomly divided into 2...

Jan 14 2026 41530950
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives.

Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...

Jan 14 2026 41532498
Externally validated knowledge-based planning model for machine learning-assisted radiation therapy treatment of high-grade glioma.

We have trained and externally validated a knowledge-based planning model for radiation therapy planning in the setting of high-grade glioma. Model pe...

Jan 14 2026 41539863
Single-inspiratory quantitative CT nomogram for enhanced PRISm and COPD differentiation: a cross-sectional study with interpretable diagnostic boundaries.

BACKGROUND: Differentiating preserved ratio impaired spirometry (PRISm) from chronic obstructive pulmonary disease (COPD) is challenging. Traditional ...

Jan 14 2026 41551461
NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells.

BACKGROUND: Glioma is the most common malignant primary brain tumor. Temozolomide (TMZ) is the standard first-line chemotherapy, but its efficacy is s...

Jan 13 2026 41534309
CT-free attenuation and scatter correction of [11C]CFT brain PET using a Bi-directional matching network.

Quantitative PET imaging requires accurate attenuation and scatter correction (ASC), but the standard CT-based method introduces additional radiation ...

Jan 13 2026 41539466
Machine learning-guided identification of metastasis-associated miRNAs and their integration into a PFI-based cox risk score and nomogram.

BACKGROUND: Metastasis drives mortality in breast invasive carcinoma. We sought miRNA biomarkers that (i) discriminate metastatic potential, (ii) stra...

Jan 11 2026 41525738
Machine learning assisted raman spectroscopy for the classification of ovarian cancer cells.

Ovarian cancer is one of the most lethal gynecological malignancies, asymptomatic early progression, ineffective screening, and high histological hete...

Jan 10 2026 41544326
Machine Learning-Based Prediction Model for Delayed Chemotherapy-Induced Nausea and Vomiting in Pediatric Cancer: A Prospective Cohort Study.

BACKGROUND: Delayed chemotherapy-induced nausea and vomiting (CINV) in pediatric oncology patients is currently under-recognized. This study aims to d...

Jan 10 2026 41518115
MRI-to-PET synthesis via deep learning for amyloid-β quantification in Alzheimer's disease.

OBJECTIVES: Amyloid-β (Aβ) PET is crucial for diagnosing and monitoring Alzheimer's disease (AD), but its high cost and radiation exposure limit its u...

Jan 7 2026 41495456
Chemo-prAIdict Breast: A deep learning solution for predicting residual disease on biopsies of breast cancer patients treated with neoadjuvant chemotherapy.

BACKGROUND: Predicting chemosensitivity before treatment could help tailor neoadjuvant chemotherapy (NAC) in early breast cancer (eBC). Pathological c...

Jan 7 2026 41518683
3D tibial HU reconstruction from biplanar X-rays utilizing a hybrid PCA-CNN framework.

High-resolution Computed Tomography (CT) is the gold standard medical imaging technique for bone assessment. However, its clinical use is limited by h...

Jan 7 2026 41506030
Advancements in radiation dose reduction for pediatric CT head Imaging: A scoping review of emerging Technologies, Protocols, and optimization strategies.

Computed tomography (CT) is an important imaging modality that provides cross-sectional images, aiding in the detailed visualization of internal struc...

Jan 6 2026 41567817
[Chronic skin damage from UV radiation].

Ultraviolet (UV) radiation is the primary risk factor for the development of both melanocytic and nonmelanocytic skin cancer. In particular, UVA and U...

Jan 6 2026 41495244
Artificial intelligence in diagnostic, prognostic, and predictive genomic biomarkers for prostate cancer: Ready for prime time?

INTRODUCTION: Until recently, the widespread use of genetic markers in prostate cancer (PCa) has been limited by the complexities and cost of genomic ...

Jan 2 2026 41483979
Anomaly detection in gamma-ray spectra using autoencoders with small form factor CZT detectors.

The detection of weak radioactive sources in fluctuating background environments is a critical task for nuclear security, environmental monitoring, an...

Dec 31 2025 41478139
Decoding Senescence-Driven Heterogeneity in Early-Onset Colorectal Cancer for Prognostic and Therapeutic Stratification.

Early-onset colorectal cancer (EOCRC), diagnosed in patients under 50, is particularly aggressive, yet lacks targeted therapeutic strategies. This stu...

Dec 28 2025 41456860
Polyploid giant cancer cells: A novel target in future cancer therapy.

Under intense therapeutic stress-including chemotherapy, radiotherapy, and targeted therapies-tumor cells can undergo ploidy reprogramming to generate...

Dec 27 2025 41496179
AI-Enabled Early Detection of Chemo-Induced Cardiotoxicity Patterns Using ECG Time Series Data: A Simulated Oncology Framework.

OBJECTIVES: Chemotherapy-induced cardiotoxicity is still a major clinical problem, usually appearing subclinically before structural or symptomatic ca...

Dec 26 2025 41449567
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