Breast Cancer

Introduction of a hybrid approach based on statistical shape model and Adaptive Neural Fuzzy Inference System (ANFIS) to assess dosimetry uncertainty: A Monte Carlo study.

The increasing use of ionizing radiation has raised concerns about adverse and long-term health risks for individuals. Therefore, to evaluate the range of risks and protection against ionizing radiation, it is necessary to assess the dosimetry calculation uncertainty of the absorbed dose of organs and tissues in the body. On the other hand, absorbed dose calculation with low computational load pla...

Development of a deep learning-based model for guiding a dissection during robotic breast surgery.

BACKGROUND: Traditional surgical education is based on observation and assistance in surgical practice. Recently introduced deep learning (DL) techniques enable the recognition of the surgical view and automatic identification of surgical landmarks. However, there was no previous studies have conducted to develop surgical guide for robotic breast surgery. To develop a DL model for guiding the diss...

Direct-to-Treatment Adaptive Radiation Therapy: Live Planning of Spine Metastases Using Novel Cone Beam Computed Tomography.

PURPOSE: Cone beam computed tomography (CBCT)-based online adaptive radiation therapy is carried out using a synthetic CT (sCT) created through deform...

Harnessing Artificial Intelligence for Precision Diagnosis and Treatment of Triple Negative Breast Cancer.

Triple-Negative Breast Cancer (TNBC) is a highly aggressive subtype of breast cancer (BC) characterized by the absence of estrogen, progesterone, and ...

Self-supervised learning reveals clinically relevant histomorphological patterns for therapeutic strategies in colon cancer.

Self-supervised learning (SSL) automates the extraction and interpretation of histopathology features on unannotated hematoxylin-eosin-stained whole s...

A new strategy to HER2-specific antibody discovery through artificial intelligence-powered phage display screening based on the Trastuzumab framework.

Human epidermal growth factor receptor 2 (HER2) is a recognized drug target, and it serves as a critical target for various cancer treatments, necessi...

Continuous nursing symptom management in cancer chemotherapy patients using deep learning.

To assess the efficacy of a deep learning platform for managing symptoms in chemotherapy patients, aiming to enhance their quality of life. A non-rand...

Accurate phenotyping of luminal A breast cancer in magnetic resonance imaging: A new 3D CNN approach.

Breast cancer (BC) remains a predominant and deadly cancer in women worldwide. By 2040, projections indicate that more than 3 million new cases of bre...

Multi-Omics Deep-Learning Prediction of Homologous Recombination Deficiency-Like Phenotype Improved Risk Stratification and Guided Therapeutic Decisions in Gynecological Cancers.

Homologous recombination deficiency (HRD) is a well-recognized important biomarker in determining the clinical benefits of platinum-based chemotherapy...

CDAF-Net: A Contextual Contrast Detail Attention Feature Fusion Network for Low-Dose CT Denoising.

Low-dose computed tomography (LDCT) is a specialized CT scan with a lower radiation dose than normal-dose CT. However, the reduced radiation dose can ...

Machine Learning Accurately Predicts Patient-reported Outcomes 1 Year After Breast Reconstruction.

OBJECTIVE: To develop and evaluate machine learning algorithms for predicting patient-reported outcomes following breast reconstruction. BACKGROUND: M...

Development of Machine Learning Models for Predicting Radiation Dermatitis in Breast Cancer Patients Using Clinical Risk Factors, Patient-Reported Outcomes, and Serum Cytokine Biomarkers.

BACKGROUND: Radiation dermatitis (RD) is a significant side effect of radiotherapy experienced by breast cancer patients. Severe symptoms include desq...

The Extent to Which Artificial Intelligence Can Help Fulfill Metastatic Breast Cancer Patient Healthcare Needs: A Mixed-Methods Study.

The Artificial Intelligence Patient Librarian (AIPL) was designed to meet the psychosocial and supportive care needs of Metastatic Breast Cancer (MBC)...

Enhancing Personalized Chemotherapy for Ovarian Cancer: Integrating Gene Expression Data with Machine Learning.

OBJECTIVE:  Ovarian cancer's complexity and heterogeneity pose significant challenges in treatment, often resulting in suboptimal chemotherapy outcome...

Artificial Intelligence in Breast Reconstruction: A Narrative Review.

Breast reconstruction following mastectomy or sectorectomy significantly impacts the quality of life and psychological well-being of breast cancer pat...

Predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients based on ultrasound longitudinal temporal depth network fusion model.

OBJECTIVE: The aim of this study was to develop and validate a deep learning radiomics (DLR) model based on longitudinal ultrasound data and clinical ...

Effectiveness of AI for Enhancing Computed Tomography Image Quality and Radiation Protection in Radiology: Systematic Review and Meta-Analysis.

BACKGROUND: Artificial intelligence (AI) presents a promising approach to balancing high image quality with reduced radiation exposure in computed tom...

Evaluation of MRI anatomy in machine learning predictive models to assess hydrogel spacer benefit for prostate cancer patients.

INTRODUCTION: Hydrogel spacers (HS) are designed to minimise the radiation doses to the rectum in prostate cancer radiation therapy (RT) by creating a...

Using prognostic signatures and machine learning to identify core features associated with response to CDK4/6 inhibitor-based therapy in metastatic breast cancer.

CDK4/6 inhibitors in combination with endocrine therapy are widely used to treat HR+/HER2- metastatic breast cancer leading to improved progression-fr...

Big data analysis and machine learning of the role of cuproptosis-related long non-coding RNAs (CuLncs) in the prognosis and immune landscape of ovarian cancer.

BACKGROUND: Ovarian cancer (OC) is a severe malignant tumor with a significant threat to women's health, characterized by a high mortality rate and po...