Oncology/Hematology

Chemotherapy

Latest AI and machine learning research in chemotherapy for healthcare professionals.

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[A Case of Locally Advanced Rectal Cancer Treated by Robot Assisted Intersphincteric Resection after Neoadjuvant Chemotherapy].

We present a case of locally advanced rectal cancer(LARC)treated by robot assisted intersphincteric resection(ISR)and lateral lymph node dissection(LLND)after neoadjuvant chemotherapy(NAC). The patient was a 69-year-old female with the diagnosis of adenocarcinoma of the rectum Rb. The clinical stage diagnosis was cT3N0M0, cStage Ⅱ. NAC with FOLFOXIRI(5-fluorouracil/oxaliplatin/leucovorin/irinoteca...

Jan 1 2021 33468749

Antimicrobial, Cytotoxic and Oxidative Stress Inhibitory Activities of Terpenoids and Flavonols from (Oliv.) P.J.H. Hurter.

(knob thorn) is a deciduous tree distributed in savannah regions from Tanzania to South Africa used for timber but also medicinally for the treatment of convulsions, wounds, and skin problems. In this study, the biological activities of six phytocompounds, namely: 3 -hydroxy-20(29)-en-lupan-30-al (), 30-hydroxylup-20(29)-en-3 -ol (), -kaur-15-en-18,20-diol (), melanoxetin (), quercetin () and q...

Jan 1 2021 35194450
[Application of artificial intelligence technology in the diagnosis and treatment of colorectal cancer].

The combination of artificial intelligence (AI) technology and medicine is an important milestone in the development of modern medicine, which realize...

Dec 25 2020 33353269
Predicting Survival After Hepatocellular Carcinoma Resection Using Deep Learning on Histological Slides.

BACKGROUND AND AIMS: Standardized and robust risk-stratification systems for patients with hepatocellular carcinoma (HCC) are required to improve ther...

Dec 1 2020 32108950
Robot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open esophagectomy: long-term follow-up of a randomized clinical trial.

Initial results of the ROBOT, which randomized between robot-assisted minimally invasive esophagectomy (RAMIE) and open transthoracic esophagectomy (O...

Nov 26 2020 33241302
[Determination of dacarbazine in the urine of mice with melanoma by high performance liquid chromatography].

Dacarbazine (DTIC) is a first-line chemotherapy drug that is widely used in clinical practice for malignant melanoma. DTIC is metabolized by the liver...

Nov 8 2020 34213101
Volatile constituents and in vitro activity of Syzygium aromaticum flower buds (clove) against human cancer cell lines.

The methanolic extract (SA-EXT) of Syzygium aromaticum flower buds and its fractions tested against three human cancer cell lines viz uterine cervix (...

Nov 1 2020 33867344
Clinically Applicable Deep Learning Framework for Measurement of the Extent of Hair Loss in Patients With Alopecia Areata.

This study aims to develop a deep learning framework to determine the Severity of Alopecia Tool (SALT) score for measurement of hair loss in patients ...

Sep 1 2020 32785607
Recent Advances of Artificial Intelligence in Cardiovascular Disease.

Cardiovascular disease (CVD) is one of the most serious health disorders with increasing prevalence and high morbidity and mortality. Although diagnos...

Jul 1 2020 33308375
[Application of convolutional neural network to risk evaluation of positive circumferential resection margin of rectal cancer by magnetic resonance imaging].

To explore the feasibility of using faster regional convolutional neural network (Faster R-CNN) to evaluate the status of circumferential resection m...

Jun 25 2020 32521977
[Efficacy of Neoadjuvant Endocrine Therapy for Prostate Ductal Carcinoma with Large Multiple Cysts Prior to Robot-Assisted Laparoscopic Radical Prostatectomy].

A 71-year-old man with gross hematuria and urinary retention showed a 7×8 cm polycystic mass compressing the prostate on the right ventral side on pel...

Apr 1 2020 32483947
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.

BACKGROUND: Improved markers of prognosis are needed to stratify patients with early-stage colorectal cancer to refine selection of adjuvant therapy. ...

Feb 1 2020 32007170
Diterpenoids from Roots of and Toxicity against Human Cancer Cell Lines.

Further investigations on phytochemical constituents of dichloromethane extract from roots of ( led to the isolation and identification of eight know...

Jan 1 2020 33841524
[A Case of Disseminated Carcinomatosis of the Bone Marrow Developing 15 Months after Gastrectomy].

The patient was a 60-year-old man who underwent distal gastrectomy for gastric cancer. The pathological diagnosis was Stage ⅡB. He received adjuvant c...

Dec 1 2019 32156888
[A Patient with Multiple Colorectal Liver Metastases for Whom Partial Splenic Embolization Contributed Extremely to Maintain Multidisciplinary Treatment].

After approximately 2.5 years of chemotherapy at the referred hospital, a 69-year-old man with double colon cancer and unresectable liver metastases(H...

Dec 1 2019 32156911
[A Case of Breast Cancer Liver Metastases with Jaundice Responding to Chemotherapy].

A 50-year-old woman was referred to our hospital due to breast cancer with multiple liver metastasis diagnosed by CT scan. Laboratory findings showed ...

Dec 1 2019 32156965
[A Case of Splenic Lymph Node Metastasis from the Distal Bile Duct Carcinoma Seven Years after a Curative Resection].

We report a case of splenic lymph node recurrence 7 years after a distal bile duct carcinoma. A 70s man underwent pylorus ring-preserving pancreaticod...

Dec 1 2019 32156969
[A Case of Two Curative Resections for the Peritoneal Dissemination of Transverse Colon Cancer].

No large clinical trials have been conducted to prove the efficacy of peritoneal dissemination resection for colorectal cancer, and no evidence has sh...

Dec 1 2019 32156971
[Rectal Gastrointestinal Stromal Tumor(GIST)Excised by Two Teams Following Neoadjuvant Chemotherapy-A Case Report].

A 67-year-old man presented with bloody stools. Colonoscopy showed a small submucosal tumor in the lower rectum. As the tumor was small, follow-up was...

Dec 1 2019 32157005
[Stage Ⅳ Breast Cancer with Difficulty in Initiating Chemotherapy-A Case Report].

We report a case of breast cancer(T4b[skin], N1, M1[lung], ER-, PR-, HER2 3+)in a 63-year-old woman with liver dysfunction of unknown cause(T-Bil 3.6m...

Dec 1 2019 32157008
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