Chemotherapy

Rumex dentatus could be a potent alternative to treatment of microbial infections and of breast cancer.

OBJECTIVE: To investigate the phytochemicals and in vitro antioxidant, antimicrobial and cytotoxic potential of Rumex dentatus (R. dentatus) leaf extracts.

Toxic activity of Prunus spinosa L. flower extract in hepatocarcinoma cells.

Prunus spinosa L. (blackthorn) is used in traditional medicine as a remedy for various diseases. To establish its anticancer properties, we exposed human liver cancer cells (Hep G2) to a range of blackthorn flower extract concentrations (10-200 µg/mL) and determined cytotoxic activity with the neutral red and kenacid blue methods after 24, 48, and 72 h of incubation. Statistically significant inhi...

In vitro cytotoxic, antioxidant, antibacterial and antifungal activity of Saussurea heteromalla indigenous to Pakistan.

Medicinal plants are proven to reveal vast promising potential providing novel drug candidates to combat health-related problems. The aim of current s...

Prior to Initiation of Chemotherapy, Can We Predict Breast Tumor Response? Deep Learning Convolutional Neural Networks Approach Using a Breast MRI Tumor Dataset.

We hypothesize that convolutional neural networks (CNN) can be used to predict neoadjuvant chemotherapy (NAC) response using a breast MRI tumor datase...

Production of Dextran from Locally Lactobacillus Spp. Isolates.

BACKGROUND: Dextran is a commercially available bacterial exopolysaccharide (EPS) with several industrial applications in the food industry and in the...

Chemical composition and antioxidant, cytotoxic, and insecticidal potential of Valeriana alliariifolia in Turkey.

Valeriana is a common plant species used for various healing purposes in folk medicine since antiquity. This study investigates the phytochemical prof...

Deep Learning Approach for Assessment of Bladder Cancer Treatment Response.

We compared the performance of different Deep learning-convolutional neural network (DL-CNN) models for bladder cancer treatment response assessment b...

Impact of Machine Learning With Multiparametric Magnetic Resonance Imaging of the Breast for Early Prediction of Response to Neoadjuvant Chemotherapy and Survival Outcomes in Breast Cancer Patients.

PURPOSE: The aim of this study was to assess the potential of machine learning with multiparametric magnetic resonance imaging (mpMRI) for the early p...

Personalized Pancreatic Cancer Management: A Systematic Review of How Machine Learning Is Supporting Decision-making.

This review critically analyzes how machine learning is being used to support clinical decision-making in the management of potentially resectable pan...

Constructing a Risk Prediction Model for Lung Cancer Recurrence by Using Gene Function Clustering and Machine Learning.

OBJECTIVE: A significant proportion of patients with early non-small cell lung cancer (NSCLC) can be cured by surgery. The distant metastasis of tumor...

Effects of Baneh () Gum on Human Breast Cancer Cell Line (MCF-7) and Its Interaction with Anticancer Drug Doxorubicin.

is one of the species of that grows in the wild in different regions of Iran. Traditionally, family has antibacterial, fungicidal, and cytotoxic pr...

Anti-cancer Potential of Captopril and Botulinum Toxin Type-A and Associated p53 Gene Apototic Stimulating Activity.

Mutational inactivation of p53 is a key player in the development of human cancer. Thus, retrieving the tumor suppressor activity of p53 gene is consi...

and Antileishmanial Activity of a Compound Derived of Platinum, Oxaliplatin, against .

This study aimed to evaluate the antileishmanial efficacy of oxaliplatin against both and . The IC, CC, and SI of oxaliplatin against promastigotes...

The Photothermal Effect of Targeted Methotrexate-Functionalized Multi-Walled Carbon Nanotubes on MCF7 Cells.

Our goal is to reduce the release rate of methotrexate (MTX) and increase cell death efficiency.Carboxylated multi-walled carbon nanotubes (MWCNT-COOH...

Large Cell Neuroendocrine Carcinoma of the Extrahepatic Bile Duct.

Primary neuroendocrine tumors originating from the extrahepatic bile duct are rare. Among these tumors, large cell neuroendocrine carcinomas (NECs) ar...

Postoperative adjuvant transarterial chemoembolization for multinodular hepatocellular carcinoma within the Barcelona Clinic Liver Cancer early stage and microvascular invasion.

BACKGROUND: The survival benefit of postoperative adjuvant transcatheter arterial chemoembolization (PA-TACE) remained controversial. We aimed to inve...

[Nephrotoxicity of a Short Hydration Method for the Cisplatin Regimen in Patients with Gastric Cancer].

BACKGROUND: S-1 plus cisplatin(CDDP)has been a key regimen for advanced gastric cancer treatment. However, CDDP confers dose-limiting nephrotoxicity, ...

[A Case of Laparoscopic Resection for Locally Advanced Primary Rectal Cancer after Neoadjuvant Chemotherapy].

We treateda 70-year-oldfemale patient with locally advancedrectal cancer accompaniedby metastases to other organs. Three courses of S-1 plus oxaliplat...

Feasibility study of stain-free classification of cell apoptosis based on diffraction imaging flow cytometry and supervised machine learning techniques.

This study was to explore the feasibility of prediction and classification of cells in different stages of apoptosis with a stain-free method based on...

Detecting Chemotherapeutic Skin Adverse Reactions in Social Health Networks Using Deep Learning.

This study reports proof-of-principle early detection of chemotherapeutic-associated skin adverse drug reactions from social health networks using a d...