Clinical Trials

Perioperative comparison between robot-assisted and laparoscopic radical cystectomy: An update meta-analysis.

We conducted this study to explore the efficacy and safety of laparoscopic radical cystectomy (LRC) and robot-assisted radical cystectomy (RARC) for bladder cancer (BC).We searched the PubMed, Embase, Cochrane Library and Web of Science databases for studies on LRC and RARC treatment of BC from the time of the databases creation to May 1, 2022. We extracted data and used Stata 16.0 for calculation...

Efficient Deep Learning Based Hybrid Model to Detect Obstructive Sleep Apnea.

An increasing number of patients and a lack of awareness about obstructive sleep apnea is a point of concern for the healthcare industry. Polysomnography is recommended by health experts to detect obstructive sleep apnea. The patient is paired up with devices that track patterns and activities during their sleep. Polysomnography, being a complex and expensive process, cannot be adopted by the majo...

Robot-Assisted Laparoscopic Radical Prostatectomy Using the KangDuo Surgical Robot System the da Vinci Si Robotic System.

To compare the efficacy and safety of robot-assisted laparoscopic radical prostatectomy (RARP) performed using the KangDuo surgical robot system to t...

15-year biochemical failure, metastasis, salvage therapy, and cancer-specific and overall survival rates in men treated with robotic radical prostatectomy for PSA-screen detected prostate cancer.

BACKGROUND: An informed decision regarding a treatment option requires data on its long-term efficacy and side-effect profile. While the side-effects ...

Virtual patients, digital twins and causal disease models: Paving the ground for in silico clinical trials.

Computational models are being explored to simulate in silico the efficacy and safety of drug candidates and medical devices. Disease models that are ...

Drainless robot-assisted minimally invasive oesophagectomy-randomized controlled trial (RESPECT).

BACKGROUND: The purpose of this randomized trial is to evaluate the early removal of postoperative drains after robot-assisted minimally invasive oeso...

Parsable Clinical Trial Eligibility Criteria Representation Using Natural Language Processing.

Successful clinical trials offer better treatments to current or future patients and advance scientific research. Clinical trials define the target po...

Methodological information extraction from randomized controlled trial publications: a pilot study.

Most biomedical information extraction (IE) approaches focus on entity types such as diseases, drugs, and genes, and relations such as gene-disease as...

Gait training with a wearable powered robot during stroke rehabilitation: a randomized parallel-group trial.

BACKGROUND: We have developed a wearable rehabilitation robot, "curara®," and examined its immediate effect in patients with spinocerebellar degenerat...

Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.

Lanthipeptides are ribosomally-synthesized natural products from bacteria featuring stable thioether-crosslinks and various bioactivities. Herein, we ...

An ensemble of AHP-EW and AE-RNN for food safety risk early warning.

Food safety problems are becoming increasingly severe in modern society, and establishing an accurate food safety risk warning and analysis model is o...

The role of warm ischemia time on functional outcomes after robotic partial nephrectomy: a radionuclide renal scan study from the clock randomized trial.

PURPOSE: To evaluate the relationship between warm ischemia time (WIT) duration and renal function after robot-assisted partial nephrectomy (RAPN).

Critical Appraisal of Artificial Intelligence-Enabled Imaging Tools Using the Levels of Evidence System.

Clinical adoption of an artificial intelligence-enabled imaging tool requires critical appraisal of its life cycle from development to implementation ...

Artificial intelligence and real-world data for drug and food safety - A regulatory science perspective.

In 2013, the Global Coalition for Regulatory Science Research (GCRSR) was established with members from over ten countries (www.gcrsr.net). One of the...

New Artificial Intelligence-Integrated Electromyography-Driven Robot Hand for Upper Extremity Rehabilitation of Patients With Stroke: A Randomized, Controlled Trial.

BACKGROUND: An artificial intelligence (AI)-integrated electromyography (EMG)-driven robot hand was devised for upper extremity (UE) rehabilitation. T...

Piloting an automated clinical trial eligibility surveillance and provider alert system based on artificial intelligence and standard data models.

BACKGROUND: To advance new therapies into clinical care, clinical trials must recruit enough participants. Yet, many trials fail to do so, leading to ...

Comparison of Transperitoneal and Retroperitoneal Partial Nephrectomy with Single-Port Robot.

To investigate the efficacy and safety of single-port (SP) robotic transperitoneal (TP) and retroperitoneal (RP) partial nephrectomy. We sequentiall...

Re: Xuesong Li, Weifeng Xu, Shubo Fan, et al. Robot-assisted Partial Nephrectomy with the Newly Developed KangDuo Surgical Robot Versus the da Vinci Si Surgical System: A Double-center Prospective Randomized Controlled Noninferiority Trial. Eur Urol Focus 2023:9:133-40.

A "Do No Harm" Novel Safety Checklist and Research Approach to Determine Whether to Launch an Artificial Intelligence-Based Medical Technology: Introducing the Biological-Psychological, Economic, and Social (BPES) Framework.

Given the impact artificial intelligence (AI)-based medical technologies (hardware devices, software programs, and mobile apps) can have on society, d...

Blinded, randomized trial of sonographer versus AI cardiac function assessment.

Artificial intelligence (AI) has been developed for echocardiography, although it has not yet been tested with blinding and randomization. Here we des...