Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Detecting cells in intravital video microscopy using a deep convolutional neural network.

The analysis of leukocyte recruitment in intravital video microscopy (IVM) is essential to the understanding of inflammatory processes. However, because IVM images often present a large variety of visual characteristics, it is hard for an expert human or even conventional machine learning techniques to detect and count the massive amount of cells and extract statistical measures precisely. Convolu...

Nov 21 2020 33285356

Using digital technologies in clinical trials: Current and future applications.

In 2015, we provided an overview of the use of digital technologies in clinical trials, both as a methodological tool and as a mechanism to deliver interventions. At that time, there was limited guidance and limited use of digital technologies in clinical research. However, since then smartphones have become ubiquitous and digital health technologies have exploded. This paper provides an update to...

Nov 17 2020 33212293
Artificial Intelligence for Surgical Safety: Automatic Assessment of the Critical View of Safety in Laparoscopic Cholecystectomy Using Deep Learning.

OBJECTIVE: To develop a deep learning model to automatically segment hepatocystic anatomy and assess the criteria defining the critical view of safety...

Nov 16 2020 33201104
Artificial intelligence for melanoma diagnosis.

Convolutional neural networks (CNN) have shown unprecedented accuracy in digital image analysis, which can be harnessed for melanoma recognition throu...

Nov 12 2020 33179882
Effect of Chronotherapy of Antihypertensives in Chronic Kidney Disease: A Randomized Control Trial.

INTRODUCTION: There is a higher prevalence of non-dipping pattern in hypertensive chronic kidney disease (CKD) patients. Nocturnal hypertension has be...

Nov 11 2020 33994681
Characterization of specific and distinct patient types in clinical trials of acute schizophrenia using an uncorrelated PANSS score matrix transform (UPSM).

Understanding the specificity of symptom change in schizophrenia can facilitate the evaluation antipsychotic efficacy for different symptom domains. P...

Nov 11 2020 33223272
Comparison of Different Dosages and Volumes of Triamcinolone in the Treatment of Stenosing Tenosynovitis: A Prospective, Blinded, Randomized Trial.

BACKGROUND: Stenosing tenosynovitis is a condition due to a size mismatch between the flexor tendons and the first annular pulley. Corticosteroid inje...

Nov 10 2020 34760843
Safety and efficacy of robot-assisted versus open pancreaticoduodenectomy: a meta-analysis of multiple worldwide centers.

The objective of the study is to compare the safety and efficacy of robot-assisted pancreaticoduodenectomy (PD) with open PD. The PubMed, EMBASE and C...

Nov 7 2020 33159662
Machine learning reduced workload with minimal risk of missing studies: development and evaluation of a randomized controlled trial classifier for Cochrane Reviews.

OBJECTIVES: This study developed, calibrated, and evaluated a machine learning classifier designed to reduce study identification workload in Cochrane...

Nov 7 2020 33171275
A Mixed-Perception Approach for Safe Human-Robot Collaboration in Industrial Automation.

Digital-enabled manufacturing systems require a high level of automation for fast and low-cost production but should also present flexibility and adap...

Nov 7 2020 33171709
Accuracy of machine learning-based prediction of medication adherence in clinical research.

Medication non-adherence represents a significant barrier to treatment efficacy. Remote, real-time measurement of medication dosing can facilitate dyn...

Nov 4 2020 33242836
Text Classification for Clinical Trial Operations: Evaluation and Comparison of Natural Language Processing Techniques.

The ability to detect patterns and trends across protocol deviations (PDs) is key to ensure high data quality and sufficient oversight of patient safe...

Oct 30 2020 33125616
Using Machine Learning to Predict Suicide Attempts in Military Personnel.

Identifying predictors of suicide attempts is critical in intervention and prevention efforts, yet finding predictors has proven difficult due to the ...

Oct 22 2020 33113452
2019 Novel Coronavirus-Infected Pneumonia on CT: A Feasibility Study of Few-Shot Learning for Computerized Diagnosis of Emergency Diseases.

COVID-19 is an emerging disease with transmissibility and severity. So far, there are no effective therapeutic drugs or vaccines for COVID-19. The mos...

Oct 22 2020 34812364
A Randomized Study Using Telepresence Robots for Behavioral Health in Interprofessional Practice and Education.

The events of the coronavirus disease 2019 (COVID-19) pandemic forced the world to adopt telemedicine frameworks to comply with isolation and stay-at...

Oct 21 2020 33090088
Regulatory Frameworks for Development and Evaluation of Artificial Intelligence-Based Diagnostic Imaging Algorithms: Summary and Recommendations.

Although artificial intelligence (AI)-based algorithms for diagnosis hold promise for improving care, their safety and effectiveness must be ensured t...

Oct 20 2020 33096088
Antibiotics are not necessary during routine cystoscopic stent removal: A randomized controlled trial at UC San Diego.

INTRODUCTION: Current American Urological Association (AUA) Best Practice Statement recommends antibiotic prophylaxis for cystoscopy with manipulation...

Oct 15 2020 33776335
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise predi...

Oct 7 2020 33027251
How to Improve Compliance with Protective Health Measures during the COVID-19 Outbreak: Testing a Moderated Mediation Model and Machine Learning Algorithms.

In the wake of the sudden spread of COVID-19, a large amount of the Italian population practiced incongruous behaviors with the protective health meas...

Oct 4 2020 33020395
easyEndo robotic endoscopy system: Development and usability test in a randomized controlled trial with novices and physicians.

BACKGROUND: Some difficulties are common when using endoscopes. Steering is not intuitive, the endoscope weight is a physical burden to physicians and...

Oct 2 2020 32875670
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